Relationship Between COVID-19 and Angiotensin-Converting Enzyme 2: A Scoping Review.

ACE2 Angiotensin converting enzyme 2 Bat-SARS-CoV COVID-19 Receiver connection range SARS-CoV SARS-CoV-2 SARS-CoV-like Spike protein

Journal

Advances in experimental medicine and biology
ISSN: 0065-2598
Titre abrégé: Adv Exp Med Biol
Pays: United States
ID NLM: 0121103

Informations de publication

Date de publication:
2021
Historique:
entrez: 3 3 2021
pubmed: 4 3 2021
medline: 6 3 2021
Statut: ppublish

Résumé

Following the outbreaks of SARS-CoV in 2002 and MERS-CoV in 2012, the COVID-19 pandemic caused by the SARS-CoV-2 virus has become an increasing threat to human health around the world. Numerous studies have shown that SARS-CoV-2 appears similar to the SARS-CoV as it uses angiotensin converting enzyme 2 (ACE2) as a receptor to gain entry into cells. The main aims of this scoping review were to identify the primary hosts of coronaviruses, the relationship between the receptor binding domain of coronaviruses and ACE2, the organ specificity of ACE2 expression compared with clinical manifestations of the disease, and to determine if this information can be used in the development of novel treatment approaches for the COVID-19 pandemic.

Identifiants

pubmed: 33656713
doi: 10.1007/978-3-030-59261-5_5
doi:

Substances chimiques

Spike Glycoprotein, Coronavirus 0
Peptidyl-Dipeptidase A EC 3.4.15.1
Angiotensin-Converting Enzyme 2 EC 3.4.17.23

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

53-68

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Auteurs

Asma Shojaee (A)

Student Research Committee, Nursing Faculty, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Amir Vahedian-Azimi (A)

Trauma Research Center, Nursing Faculty, Baqiyatallah University of Medical Sciences, Tehran, Iran. amirvahedian63@gmail.com.

Fakhrudin Faizi (F)

Atherosclerosis research center, Nursing Faculty, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Farshid Rahimi-Bashar (F)

Anesthesia and Critical Care Department, Hamadan University of Medical Sciences, Hamadan, Iran.

Alireza Shahriary (A)

Chemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Hadi Esmaeili Gouvarchin Galeh (HEG)

Applied virology research center, Baqiyatallah University of medical science, Tehran, Iran.

Batool Nehrir (B)

Health Management Research Center, Nursing Faculty, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Paul C Guest (PC)

Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil.

Amirhossein Sahebkar (A)

Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. amir_saheb2000@yahoo.com.
Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran. amir_saheb2000@yahoo.com.
Polish Mother's Memorial Hospital Research Institute (PMMHRI), Lodz, Poland. amir_saheb2000@yahoo.com.
Halal Research Center of IRI, FDA, Tehran, Iran. amir_saheb2000@yahoo.com.

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