Relationship Between COVID-19 and Angiotensin-Converting Enzyme 2: A Scoping Review.
ACE2
Angiotensin converting enzyme 2
Bat-SARS-CoV
COVID-19
Receiver connection range
SARS-CoV
SARS-CoV-2
SARS-CoV-like
Spike protein
Journal
Advances in experimental medicine and biology
ISSN: 0065-2598
Titre abrégé: Adv Exp Med Biol
Pays: United States
ID NLM: 0121103
Informations de publication
Date de publication:
2021
2021
Historique:
entrez:
3
3
2021
pubmed:
4
3
2021
medline:
6
3
2021
Statut:
ppublish
Résumé
Following the outbreaks of SARS-CoV in 2002 and MERS-CoV in 2012, the COVID-19 pandemic caused by the SARS-CoV-2 virus has become an increasing threat to human health around the world. Numerous studies have shown that SARS-CoV-2 appears similar to the SARS-CoV as it uses angiotensin converting enzyme 2 (ACE2) as a receptor to gain entry into cells. The main aims of this scoping review were to identify the primary hosts of coronaviruses, the relationship between the receptor binding domain of coronaviruses and ACE2, the organ specificity of ACE2 expression compared with clinical manifestations of the disease, and to determine if this information can be used in the development of novel treatment approaches for the COVID-19 pandemic.
Identifiants
pubmed: 33656713
doi: 10.1007/978-3-030-59261-5_5
doi:
Substances chimiques
Spike Glycoprotein, Coronavirus
0
Peptidyl-Dipeptidase A
EC 3.4.15.1
Angiotensin-Converting Enzyme 2
EC 3.4.17.23
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
53-68Références
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