Early- and late-onset postpartum depression exhibit distinct associated factors: the IGEDEPP prospective cohort study.


Journal

BJOG : an international journal of obstetrics and gynaecology
ISSN: 1471-0528
Titre abrégé: BJOG
Pays: England
ID NLM: 100935741

Informations de publication

Date de publication:
Sep 2021
Historique:
accepted: 09 02 2021
pubmed: 4 3 2021
medline: 1 9 2021
entrez: 3 3 2021
Statut: ppublish

Résumé

To identify risk factors for early- and late-onset postpartum depression (PPD) among a wide range of variables, including sociodemographic characteristics, childhood trauma, stressful life events during pregnancy and history of personal and family psychiatric disorders, and to assess the contribution of each risk factor. Nested case-control study in a prospective longitudinal cohort study. Eight maternity departments in the Paris metropolitan area, France. A cohort of 3310 women with deliveries between November 2011 and June 2016. Cases were women with early- or late-onset PPD. Controls were women without depression during pregnancy or the postpartum period. Logistic regression adjusted on sociodemographic variables was performed for each outcome and a multivariable model was proposed based on a stepwise selection procedure. Early- and late-onset PPD assessed at 2 months and 1 year postpartum, respectively. Stressful life events during pregnancy have a dose-response relationship with both early- and late-onset PPD. Early- and late-onset PPD presented distinct patterns of determinants. These results have important consequences in terms of prevention and specific care. Early- and late-onset postpartum depression are associated with stressful life events and psychiatric history.

Identifiants

pubmed: 33656796
doi: 10.1111/1471-0528.16688
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

1683-1693

Subventions

Organisme : Programme Hospitalier de Recherche Clinique - PHRC 2010 (French Ministry of Health)
Organisme : Assistance Publique - Hôpitaux de Paris (Délégation à la Recherche Clinique et à l'Innovation)

Investigateurs

Emmanuelle Bertin (E)
Cecile Bourneuf (C)
Jeanne Colombe (J)
Laura Couppa (L)
Fanny Georges (F)
Celine Hebbache (C)
Marie Le Bars (M)
Julie Guiot Madhavi (JG)
Cindy Parent (C)
Alix de Premorel (A)

Informations de copyright

© 2021 John Wiley & Sons Ltd.

Références

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Auteurs

S Tebeka (S)

INSERM U1266, Université de Paris, Paris, France.
Department of Psychiatry, AP-HP, Louis Mourier Hospital, Colombes, France.

Y Le Strat (Y)

INSERM U1266, Université de Paris, Paris, France.
Department of Psychiatry, AP-HP, Louis Mourier Hospital, Colombes, France.

L Mandelbrot (L)

Departement Hospitalier Universitaire Risks in Pregnancy, Université de Paris, Paris, France.
Department of Obstetrics and Gynecology, AP-HP, Louis Mourier Hospital, Colombes, France.

A Benachi (A)

Université Paris Saclay, Clamart, France.
Department of Obstetrics and Gynecology, AP-HP, Antoine Beclere Hospital, Clamart, France.

M Dommergues (M)

Sorbonne University, Paris, France.
Department of Obstetrics and Gynecology, AP-HP, Hôpital Universitaire Pitié-Salpêtrière, Paris, France.

G Kayem (G)

Sorbonne University, Paris, France.
Department of Obstetrics and Gynecology, AP-HP, Trousseau Hospital, Paris, France.

J Lepercq (J)

Departement Hospitalier Universitaire Risks in Pregnancy, Université de Paris, Paris, France.
Port-Royal Maternity Unit, AP-HP, Cochin Hospital, Paris, France.

D Luton (D)

Departement Hospitalier Universitaire Risks in Pregnancy, Université de Paris, Paris, France.
Department of Obstetrics and Gynecology, AP-HP, Bichat Hospital, Paris, France.

Y Ville (Y)

Sorbonne University, Paris, France.
Department of Obstetrics and Gynecology, AP-HP, Necker Enfant Malade Hospital, Paris, France.

N Ramoz (N)

INSERM U1266, Université de Paris, Paris, France.

J Mullaert (J)

Department of Epidemiology, Biostatistics and Clinical Research, AP-HP, Hôpital Bichat, Paris, France.
IAME, INSERM, Université de Paris, Paris, France.

C Dubertret (C)

INSERM U1266, Université de Paris, Paris, France.
Department of Psychiatry, AP-HP, Louis Mourier Hospital, Colombes, France.

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