Peripheral ulcerative keratitis.
Mooren ulcer
Mooren's ulcer
PUK
Peripheral ulcerative keratitis
peripheral keratitis
Journal
Survey of ophthalmology
ISSN: 1879-3304
Titre abrégé: Surv Ophthalmol
Pays: United States
ID NLM: 0404551
Informations de publication
Date de publication:
Historique:
received:
11
08
2020
revised:
17
02
2021
accepted:
23
02
2021
pubmed:
4
3
2021
medline:
31
3
2022
entrez:
3
3
2021
Statut:
ppublish
Résumé
Peripheral ulcerative keratitis (PUK) is an inflammatory condition of the peripheral cornea with hallmark features of epithelial defects and stromal destruction as a result of a complex interplay of factors including host autoimmunity and the peculiar anatomic and physiologic features of the peripheral cornea and environmental factors. PUK may be the result of local or systemic causes and infectious or noninfectious causes. Arriving at a specific etiological diagnosis requires a meticulous clinical workup that may include a battery of laboratory and radiological investigations. Management by a team of internists or rheumatologists and ophthalmologists and judicious use of immunosuppressive agents may yield favorable results minimizing adverse effects. We review current clinical knowledge on the diagnosis and management of PUK.
Identifiants
pubmed: 33657431
pii: S0039-6257(21)00067-9
doi: 10.1016/j.survophthal.2021.02.013
pii:
doi:
Substances chimiques
Immunosuppressive Agents
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
977-998Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.