The risk of dementia after coronary artery bypass grafting in relation to age and sex.
Alzheimer's disease
coronary artery bypass grafting
dementia
vascular dementia
Journal
Alzheimer's & dementia : the journal of the Alzheimer's Association
ISSN: 1552-5279
Titre abrégé: Alzheimers Dement
Pays: United States
ID NLM: 101231978
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
revised:
28
10
2020
received:
17
06
2020
accepted:
01
11
2020
pubmed:
5
3
2021
medline:
16
11
2021
entrez:
4
3
2021
Statut:
ppublish
Résumé
We examined the long-term risk of dementia after coronary artery bypass grafting (CABG) in relation to age and sex. All CABG patients in Sweden 1992-2015 (n = 111,335), and matched controls (n = 222,396) were included in a population-based study. Adjusted hazard ratios (aHR) for all-cause dementia, vascular dementia, and Alzheimer's disease were calculated. There was no difference in the risk for all-cause dementia between CABG patients and control subjects (aHR 0.98 [95% confidence interval 0.95 to 1.02]). CABG patients <65 years and 65 to 74 years had higher risk (aHR 1.29 [1.17-1.42] and 1.08 [1.02-1.13], respectively), and patients ≥75 years had lower risk (aHR 0.76 [0.71-0.81]). The highest risk was observed in women <65 years (aHR 1.64 [1.31-2.05]). Overall, the long-term risk for all-cause dementia does not differ between CABG patients and the general population. Younger patients have a higher risk, while older patients have a lower risk, compared to controls.
Identifiants
pubmed: 33663018
doi: 10.1002/alz.12251
pmc: PMC8251974
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1042-1050Informations de copyright
© 2020 The Authors. Alzheimer's & Dementia published by Wiley Periodicals, Inc. on behalf of Alzheimer's Association.
Références
Alzheimer Dis Assoc Disord. 2017 Apr-Jun;31(2):120-127
pubmed: 28263191
Anesthesiology. 2016 Jul;125(1):62-71
pubmed: 27127919
Circulation. 2018 Feb 6;137(6):567-577
pubmed: 29025764
Heart. 2010 Oct;96(20):1617-21
pubmed: 20801780
Biomed Res Int. 2014;2014:908915
pubmed: 25089278
J Alzheimers Dis. 2019;68(2):459-471
pubmed: 30775980
Alzheimers Dement. 2020 Jun;16(6):908-917
pubmed: 32342671
Int J Cardiol. 2017 Oct 1;244:316-321
pubmed: 28784449
Interact Cardiovasc Thorac Surg. 2018 Jul 1;27(1):67-74
pubmed: 29452368
Curr Drug Targets. 2018;19(9):1038-1044
pubmed: 29623835
N Engl J Med. 2016 Sep 8;375(10):e22
pubmed: 27602683
Neurology. 2018 Apr 10;90(15):e1298-e1305
pubmed: 29540588
Int J Cardiol. 2019 Aug 15;289:43-49
pubmed: 31078353
CNS Spectr. 2004 Oct;9(10):763-72
pubmed: 15448586
Lancet. 2007 Oct 20;370(9596):1453-7
pubmed: 18064739
N Engl J Med. 2001 Feb 8;344(6):395-402
pubmed: 11172175
Lancet. 2017 Dec 16;390(10113):2673-2734
pubmed: 28735855
Nephrol Dial Transplant. 2013 Nov;28(11):2670-7
pubmed: 23975843
Neurology. 2005 Oct 11;65(7):986-90
pubmed: 16217048
Lancet Psychiatry. 2016 Jul;3(7):628-35
pubmed: 27138970
Int J Geriatr Psychiatry. 2006 Jun;21(6):509-18
pubmed: 16645936
Alzheimers Dement. 2021 Jun;17(6):1042-1050
pubmed: 33663018
BMC Public Health. 2011 Jun 09;11:450
pubmed: 21658213
Ann Thorac Surg. 2008 Jan;85(1):60-4
pubmed: 18154780
JAMA Psychiatry. 2018 Jul 1;75(7):723-732
pubmed: 29799983
Eur J Heart Fail. 2017 Feb;19(2):253-260
pubmed: 27612177