Non-apnea sleep disorder and its risk for all kinds of injuries: A 14-year follow-up for a nationwide population-based retrospective study.


Journal

Medicine
ISSN: 1536-5964
Titre abrégé: Medicine (Baltimore)
Pays: United States
ID NLM: 2985248R

Informations de publication

Date de publication:
26 Feb 2021
Historique:
received: 12 10 2020
accepted: 26 01 2021
entrez: 5 3 2021
pubmed: 6 3 2021
medline: 17 3 2021
Statut: ppublish

Résumé

Non-apnea sleep disorder (NASD) increases the risk of motor vehicle accidents. However, systemic review of NASD and its risk for all causes of injury is lacking. The aim of the present study was to provide a detailed demographic data on NASD and all causes of injury in a 14-year follow up.Our study utilized outpatient and inpatient data from the Longitudinal Health Insurance Database between 2000 and 2013 in Taiwan. We enrolled 989,753 individuals aged ≥20 years who were diagnosed with NASD as outpatients ≥3 times or inpatients ≥1 time. We matched the study cohort with a comparison cohort by age, index date and comorbidities at a ratio of 1:4. We used Cox proportional hazards regression to analyze the association of NASD and the cause of injury.In this 14-year follow up study, patients with NASD had 12.96% increased risk of injury compared to that of the control cohort. Fall was the first place of the cause of injury with 670.26 per 105 PYs. In the stratified age group, patients aged ≧65 years had the highest risk of injury (adjusted HR= 1.381; P < .001). Kaplan-Meier analysis showed that the incidence of injury between the with- and without-NASD cohorts started from the first year and persisted until the end of the follow-up.Our study demonstrates that NASD patients were associated with higher risk of all causes of injuries, with falling being the most prevalent diagnosis. The general public should be more aware of this neglected issue of NASD.

Identifiants

pubmed: 33663092
doi: 10.1097/MD.0000000000024766
pii: 00005792-202102260-00055
pmc: PMC7909222
doi:

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

e24766

Subventions

Organisme : Tri-Service General Hospital (TW)
ID : TSGH-B-110012

Informations de copyright

Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

Déclaration de conflit d'intérêts

The authors have no conflicts of interests to disclose.

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Auteurs

Zhu Wei Lim (ZW)

Department of Obstetrics and Gynecology, Changhua Christian Hospital, Changhua.

I-Duo Wang (ID)

Department of Internal Medicine, Tri-Service General Hospital.

Feng-Cheng Liu (FC)

Division of Rheumatology/Immunology and Allergy, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114.

Chi-Hsiang Chung (CH)

Department of Medical Research, Tri-Service General Hospital.
School of Public Health, National Defense Medical Center, Taipei.

Je-Ming Hu (JM)

Division of Colorectal Surgery, Department of Surgery.

Pei-Yi Tsai (PY)

Department of Radiation Oncology.

Wu-Chien Chien (WC)

Department of Medical Research, Tri-Service General Hospital.
School of Public Health, National Defense Medical Center, Taipei.
Graduate Institute of Life Sciences, National Defense Medical Center, Taipei 114, Taiwan.

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