Biguanide-Based Synthesis of 1,3,5-Triazine Derivatives with Anticancer Activity and 1,3,5-Triazine Incorporated Calcium Citrate Nanoparticles.


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
15 Feb 2021
Historique:
received: 25 01 2021
revised: 11 02 2021
accepted: 12 02 2021
entrez: 6 3 2021
pubmed: 7 3 2021
medline: 10 4 2021
Statut: epublish

Résumé

Twelve derivatives of biguanide-derived 1,3,5-triazines, a promising class of anticancer agent, were synthesised and evaluated for their anticancer activity against two colorectal cancer cell lines-HCT116 and SW620.

Identifiants

pubmed: 33672071
pii: molecules26041028
doi: 10.3390/molecules26041028
pmc: PMC7919653
pii:
doi:

Substances chimiques

Antineoplastic Agents 0
Biguanides 0
Triazines 0
Calcium Citrate MLM29U2X85

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Chulalongkorn University
ID : CU_GR_63_159_23_25
Organisme : Chulalongkorn University
ID : 72nd Anniversary of His Majesty King Bhumibol Adulyadej Scholarship
Organisme : Chulalongkorn University
ID : 90th Anniversary Chulalongkorn University Fund (Ratchadapiseksomphot Endowment Fund)

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Auteurs

Monnaya Chalermnon (M)

Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.

Sarocha Cherdchom (S)

Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Phayathai Road, Wangmai, Patumwan, Bangkok 10330, Thailand.
NanoMedicine Research Unit, Department of Anatomy, Faculty of Medicine, Chulalongkorn University, Rama 4 Road, Patumwan, Bangkok 10330, Thailand.

Amornpun Sereemaspun (A)

Chula Medical Innovation Centre (CMIC), Nanomedicine Research Unit, Department of Anatomy, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.

Rojrit Rojanathanes (R)

Centre of Excellence in Materials and Bio-Interfaces, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.

Tanatorn Khotavivattana (T)

Centre of Excellence in Natural Products Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.

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Classifications MeSH