Neonatal lupus erythematosus presenting as orolabial ulcerations: Two cases and a review of the literature.


Journal

Pediatric dermatology
ISSN: 1525-1470
Titre abrégé: Pediatr Dermatol
Pays: United States
ID NLM: 8406799

Informations de publication

Date de publication:
May 2021
Historique:
pubmed: 7 3 2021
medline: 8 7 2021
entrez: 6 3 2021
Statut: ppublish

Résumé

We report two unrelated infants who presented with orolabial ulcerations as a presenting manifestation of neonatal lupus erythematosus (NLE). Subsequent positive anti-SSA/SSB titers confirmed the diagnosis. In both infants, the ulcerations were painless and spontaneously resolved. NLE should be included in the differential diagnosis of orolabial ulcerations in the newborn, especially since mothers of affected infants may be asymptomatic.

Identifiants

pubmed: 33675085
doi: 10.1111/pde.14555
doi:

Substances chimiques

Antibodies, Antinuclear 0

Types de publication

Case Reports Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

643-646

Informations de copyright

© 2021 Wiley Periodicals LLC.

Références

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Neiman AR, Lee LA, Weston WL, Buyon JP. Cutaneous manifestations of neonatal lupus without heart block: characteristics of mothers and children enrolled in a national registry. J Pediatr. 2000;137(5):674-680.
Vanoni F, Lava SAG, Fossali EF, et al. Neonatal systemic lupus erythematosus syndrome: a comprehensive review. Clin Rev Allergy Immunol. 2017;53(3):469-476.
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Auteurs

Alex Drohan (A)

College of Medicine, Medical University of South Carolina, Charleston, SC, USA.

Alan Snyder (A)

College of Medicine, Medical University of South Carolina, Charleston, SC, USA.

John Plante (J)

School of Medicine, University of South Carolina, Columbia, SC, USA.

Samantha Karlin (S)

Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, SC, USA.

Lara Wine Lee (L)

Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, SC, USA.
Department of Pediatrics, Medical University of South Carolina, Charleston, SC, USA.

Colleen H Cotton (CH)

Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, SC, USA.
Department of Pediatrics, Medical University of South Carolina, Charleston, SC, USA.

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Classifications MeSH