Long-term safety and efficacy of givinostat in polycythemia vera: 4-year mean follow up of three phase 1/2 studies and a compassionate use program.
Journal
Blood cancer journal
ISSN: 2044-5385
Titre abrégé: Blood Cancer J
Pays: United States
ID NLM: 101568469
Informations de publication
Date de publication:
06 03 2021
06 03 2021
Historique:
received:
17
11
2020
accepted:
19
02
2021
revised:
18
02
2021
entrez:
7
3
2021
pubmed:
8
3
2021
medline:
8
1
2022
Statut:
epublish
Résumé
Polycythemia vera (PV) is a BCR-ABL1-negative myeloproliferative neoplasm (MPN) characterized by excessive proliferation of erythroid, myeloid, and megakaryocytic components in the bone marrow, mainly due to a Janus kinase 2 gene mutation (JAK2
Identifiants
pubmed: 33677466
doi: 10.1038/s41408-021-00445-z
pii: 10.1038/s41408-021-00445-z
pmc: PMC7936975
doi:
Substances chimiques
Carbamates
0
Histone Deacetylase Inhibitors
0
givinostat
5P60F84FBH
Types de publication
Clinical Trial, Phase I
Clinical Trial, Phase II
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
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