Silicone-hydrocoated ureteral stents encrustation and biofilm formation after 3-week dwell time: results of a prospective randomized multicenter clinical study.


Journal

World journal of urology
ISSN: 1433-8726
Titre abrégé: World J Urol
Pays: Germany
ID NLM: 8307716

Informations de publication

Date de publication:
Sep 2021
Historique:
received: 22 11 2020
accepted: 19 02 2021
pubmed: 11 3 2021
medline: 29 1 2022
entrez: 10 3 2021
Statut: ppublish

Résumé

To explore the risk of encrustation and biofilm formation for silicone ureteral stents compared to percuflex polymer stents, through a randomized multicenter study. Design, setting and participants: A Multicenter, prospective, randomized, single blind, comparative study of hydrocoated silicone stent (Coloplast Imajin 119 stents were available after removal for analysis, 56 in the silicone and 63 in the Percuflex TM Plus group. Mean dwelling duration was 21.8 days for silicone, 22.1 days for PercuflexTM Plus. There was significantly more biofilm on Percuflex™ Plus compared to silicone (1.24 ± 0.08 vs 0.93 ± 0.09, p = 0.0021), and more mineral encrustation (1.22 ± 0.10 vs 0.78 ± 0.11, p = 0.0048), respectively. This multicenter randomized study shows that silicone-hydrocoated stents are less prone to encrustation than PercuflexTM Plus after a 3-week dwelling period and confirms the low encrustation potential of silicone.

Identifiants

pubmed: 33688992
doi: 10.1007/s00345-021-03646-0
pii: 10.1007/s00345-021-03646-0
doi:

Substances chimiques

Coated Materials, Biocompatible 0
Polymers 0
Silicones 0
percuflex TM 0

Types de publication

Comparative Study Journal Article Multicenter Study Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

3623-3629

Informations de copyright

© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Références

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Auteurs

Yazeed Barghouthy (Y)

GRC n°20, Groupe de Recherche Clinique Sur la Lithiase Urinaire, Hôpital Tenon, Sorbonne Université, 75020, Paris, France.
Service d'Urologie, Assistance-Publique Hôpitaux de Paris, Hôpital Tenon, Sorbonne Université, 4 rue de la Chine, 75020, Paris, France.

Oliver Wiseman (O)

Urology Department, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

Eugenio Ventimiglia (E)

GRC n°20, Groupe de Recherche Clinique Sur la Lithiase Urinaire, Hôpital Tenon, Sorbonne Université, 75020, Paris, France.
Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.

Julien Letendre (J)

Urology, Maisonneuve-Rosemont Hospital, 5345 Blvd de L'Assomption, Bureau 220, Montreal, QC, Canada.

Jonathan Cloutier (J)

Urology, University Hospital Centre of Quebec City, 10 rue de l'Espinay, Quebec, QC, Canada.

Michel Daudon (M)

AP-HP, Hôpital Tenon, 75020, Paris, France.

Francois Kleinclauss (F)

Department of Urology and Renal Transplantation, CHRU Besancon, 25000, Besancon, France.

Steeve Doizi (S)

GRC n°20, Groupe de Recherche Clinique Sur la Lithiase Urinaire, Hôpital Tenon, Sorbonne Université, 75020, Paris, France.
Service d'Urologie, Assistance-Publique Hôpitaux de Paris, Hôpital Tenon, Sorbonne Université, 4 rue de la Chine, 75020, Paris, France.

Mariela Corrales (M)

GRC n°20, Groupe de Recherche Clinique Sur la Lithiase Urinaire, Hôpital Tenon, Sorbonne Université, 75020, Paris, France.
Service d'Urologie, Assistance-Publique Hôpitaux de Paris, Hôpital Tenon, Sorbonne Université, 4 rue de la Chine, 75020, Paris, France.

Olivier Traxer (O)

GRC n°20, Groupe de Recherche Clinique Sur la Lithiase Urinaire, Hôpital Tenon, Sorbonne Université, 75020, Paris, France. olivier.traxer@aphp.fr.
Service d'Urologie, Assistance-Publique Hôpitaux de Paris, Hôpital Tenon, Sorbonne Université, 4 rue de la Chine, 75020, Paris, France. olivier.traxer@aphp.fr.

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