Endothelial-Specific Deletion of CD146 Protects Against Experimental Glomerulonephritis in Mice.

Animals CD146 Antigen / genetics Disease Models, Animal Drug Discovery Endothelial Cells / metabolism Fibrosis / metabolism Gene Knockout Techniques / methods Glomerulonephritis / immunology Inflammation / metabolism Intercellular Junctions / immunology Kidney Glomerulus / immunology Mice Up-Regulation
fibrosis inflammation mice monocyte proteinuria

Journal

Hypertension (Dallas, Tex. : 1979)
ISSN: 1524-4563
Titre abrégé: Hypertension
Pays: United States
ID NLM: 7906255

Informations de publication

Date de publication:
04 2021
Historique:
entrez: 10 3 2021
pubmed: 11 3 2021
medline: 7 9 2021
Statut: ppublish

Résumé

[Figure: see text].

Identifiants

DOI: 10.1161/HYPERTENSIONAHA.119.14176 PMID: 33689459
pubmed: 33689459
doi: 10.1161/HYPERTENSIONAHA.119.14176
doi:

Substances chimiques

CD146 Antigen 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1260-1272

Auteurs

Ahmed Abed (A)

From the INSERM UMR-S1155, Tenon Hospital, Paris, France (A.A., P.K., F.A., M.G., C.E.C.).
Sorbonne Université, Paris, France (A.A., C.E.C.).

Aurélie S Leroyer (AS)

Aix-Marseille University, INSERM 1263, INRAE 1260, C2VN, France (A.S.L., R.B., A.F.-B., N.B., A.J., N.J.-C., S.B., M.B.-C., F.D.-G.).

Panagiotis Kavvadas (P)

From the INSERM UMR-S1155, Tenon Hospital, Paris, France (A.A., P.K., F.A., M.G., C.E.C.).

Florence Authier (F)

From the INSERM UMR-S1155, Tenon Hospital, Paris, France (A.A., P.K., F.A., M.G., C.E.C.).

Richard Bachelier (R)

Aix-Marseille University, INSERM 1263, INRAE 1260, C2VN, France (A.S.L., R.B., A.F.-B., N.B., A.J., N.J.-C., S.B., M.B.-C., F.D.-G.).

Alexandrine Foucault-Bertaud (A)

Aix-Marseille University, INSERM 1263, INRAE 1260, C2VN, France (A.S.L., R.B., A.F.-B., N.B., A.J., N.J.-C., S.B., M.B.-C., F.D.-G.).

Nathalie Bardin (N)

Aix-Marseille University, INSERM 1263, INRAE 1260, C2VN, France (A.S.L., R.B., A.F.-B., N.B., A.J., N.J.-C., S.B., M.B.-C., F.D.-G.).

Clemens D Cohen (CD)

Nephrological Center, Medical Clinic and Policlinic IV, University of Munich, Germany (C.D.C.).

Maja T Lindenmeyer (MT)

Department of Medicine, University Medical Center Hamburg-Eppendorf, Germany (M.T.L.).

Magali Genest (M)

From the INSERM UMR-S1155, Tenon Hospital, Paris, France (A.A., P.K., F.A., M.G., C.E.C.).

Ahmad Joshkon (A)

Aix-Marseille University, INSERM 1263, INRAE 1260, C2VN, France (A.S.L., R.B., A.F.-B., N.B., A.J., N.J.-C., S.B., M.B.-C., F.D.-G.).

Noémie Jourde-Chiche (N)

Aix-Marseille University, INSERM 1263, INRAE 1260, C2VN, France (A.S.L., R.B., A.F.-B., N.B., A.J., N.J.-C., S.B., M.B.-C., F.D.-G.).
Department of Nephrology, Aix-Marseille University, AP-HM Hôpital de la Conception, Marseille, France (N.J.-C., S.B.).

Stéphane Burtey (S)

Aix-Marseille University, INSERM 1263, INRAE 1260, C2VN, France (A.S.L., R.B., A.F.-B., N.B., A.J., N.J.-C., S.B., M.B.-C., F.D.-G.).
Department of Nephrology, Aix-Marseille University, AP-HM Hôpital de la Conception, Marseille, France (N.J.-C., S.B.).

Marcel Blot-Chabaud (M)

Aix-Marseille University, INSERM 1263, INRAE 1260, C2VN, France (A.S.L., R.B., A.F.-B., N.B., A.J., N.J.-C., S.B., M.B.-C., F.D.-G.).

Françoise Dignat-George (F)

Aix-Marseille University, INSERM 1263, INRAE 1260, C2VN, France (A.S.L., R.B., A.F.-B., N.B., A.J., N.J.-C., S.B., M.B.-C., F.D.-G.).

Christos E Chadjichristos (CE)

From the INSERM UMR-S1155, Tenon Hospital, Paris, France (A.A., P.K., F.A., M.G., C.E.C.).
Sorbonne Université, Paris, France (A.A., C.E.C.).

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Endothelial-Specific Deletion of CD146...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Antigènes de surface › Molécules d'adhérence cellulaire › Antigènes CD146 › Endothelial-Specific Deletion of CD146...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Endothelial-Specific Deletion of CD146...
questionsmedicales.fr › Techniques d'investigation › Développement de médicament › Découverte de médicament › Endothelial-Specific Deletion of CD146...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules endothéliales › Endothelial-Specific Deletion of CD146...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Fibrose › Endothelial-Specific Deletion of CD146...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Ciblage de gène › Techniques de knock-out de gènes › Endothelial-Specific Deletion of CD146...
questionsmedicales.fr › Maladies urogénitales › Maladies urologiques › Maladies du rein › Néphrite › Glomérulonéphrite › Endothelial-Specific Deletion of CD146...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Endothelial-Specific Deletion of CD146...
questionsmedicales.fr › Cellules › Structures cellulaires › Membrane cellulaire › Structures de la membrane cellulaire › Jonctions intercellulaires › Endothelial-Specific Deletion of CD146...
questionsmedicales.fr › Appareil urogénital › Voies urinaires › Rein › Néphrons › Glomérule rénal › Endothelial-Specific Deletion of CD146...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Endothelial-Specific Deletion of CD146...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Régulation positive › Endothelial-Specific Deletion of CD146...