The relationship of extent of initial radiological involvement with the need of intensive care, mortality rates, and laboratory parameters in Covid-19


Journal

Turkish journal of medical sciences
ISSN: 1303-6165
Titre abrégé: Turk J Med Sci
Pays: Turkey
ID NLM: 9441758

Informations de publication

Date de publication:
28 06 2021
Historique:
received: 03 09 2020
accepted: 02 03 2021
entrez: 11 3 2021
pubmed: 12 3 2021
medline: 6 7 2021
Statut: epublish

Résumé

It is very important for the efficient use of limited capacity and the success of treatment to predict patients who may need ICU with high mortality rate in the Covid-19 outbreak. In our study, it was aimed to investigate the value of the radiological involvement on initial CT in demonstrating the ICU transfer and mortality rate of patients. All PCR-positive patients were included in the study, whose CT, PCR, and laboratory values were obtained simultaneously at the time of first admission. Patients were divided into 4 groups in terms of the extent of radiological lesions. These groups were compared in terms of intensive care transfer needs and Covid-related mortality rates. A total of 477 patients were included in the study. Ninety of them were group 0 (no lung involvement), 162 were group 1 (mild lesion), 89 were group 2 (moderate lesion), and 136 were group 3 (severe lung involvement). A significant relationship was found between the extensiveness of the radiological lesion on CT and admission to intensive care and mortality rate. As the initial radiological involvement amounts increased, the rate of ICU transfer and mortality increased. The mortality rates of the groups were 0%, 3%, 12.3%, and 12.5%, respectively, and the difference was significant (p < 0.001). Similarly, the ICU transfer rates of the groups were 2.2%, 5.6%, 13.5%, and 17.7%, respectively, and the difference was significant (p < 0.001). In conclusion, in our study, the strong relationship between the initial radiological extent assessment and the need for intensive care and mortality rates has been demonstrated, and we believe that our results will make a significant contribution to increase the success of the health system in predicting patients who may progress, helping clinicians and managing pandemics.

Sections du résumé

Background/aim
It is very important for the efficient use of limited capacity and the success of treatment to predict patients who may need ICU with high mortality rate in the Covid-19 outbreak. In our study, it was aimed to investigate the value of the radiological involvement on initial CT in demonstrating the ICU transfer and mortality rate of patients.
Materials and methods
All PCR-positive patients were included in the study, whose CT, PCR, and laboratory values were obtained simultaneously at the time of first admission. Patients were divided into 4 groups in terms of the extent of radiological lesions. These groups were compared in terms of intensive care transfer needs and Covid-related mortality rates.
Results
A total of 477 patients were included in the study. Ninety of them were group 0 (no lung involvement), 162 were group 1 (mild lesion), 89 were group 2 (moderate lesion), and 136 were group 3 (severe lung involvement). A significant relationship was found between the extensiveness of the radiological lesion on CT and admission to intensive care and mortality rate. As the initial radiological involvement amounts increased, the rate of ICU transfer and mortality increased. The mortality rates of the groups were 0%, 3%, 12.3%, and 12.5%, respectively, and the difference was significant (p < 0.001). Similarly, the ICU transfer rates of the groups were 2.2%, 5.6%, 13.5%, and 17.7%, respectively, and the difference was significant (p < 0.001).
Conclusion
In conclusion, in our study, the strong relationship between the initial radiological extent assessment and the need for intensive care and mortality rates has been demonstrated, and we believe that our results will make a significant contribution to increase the success of the health system in predicting patients who may progress, helping clinicians and managing pandemics.

Identifiants

pubmed: 33705639
doi: 10.3906/sag-2009-49
pmc: PMC8283482
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1012-1020

Informations de copyright

This work is licensed under a Creative Commons Attribution 4.0 International License.

Déclaration de conflit d'intérêts

The authors declare no conflicts of interest that may have influenced either the conduct or the presentation of the research. No funding has been received for this paper.

Références

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Auteurs

Yusuf Aydemir (Y)

Department of Pulmonology, Faculty of Medicine, Sakarya University, Sakarya, Turkey

Yasemin Gündüz (Y)

Department of Radiology, Faculty of Medicine, Sakarya University, Sakarya, Turkey

Mehmet Köroğlu (M)

Department of Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Turkey

Oğuz Karabay (O)

Department of Infectious Diseases, Faculty of Medicine, Sakarya University, Sakarya, Turkey

Hamad Dheir (H)

Department of Nephrology, Faculty of Medicine, Sakarya University, Sakarya, Turkey

Aysun Şengül (A)

Department of Pulmonology, Faculty of Medicine, Sakarya University, Sakarya, Turkey

Selçuk Yaylacı (S)

Department of Internal Medicine, Faculty of Medicine, Sakarya University, Sakarya, Turkey

Havva Kocayiğit (H)

Department of Anesthesiology and Reanimation, Faculty of Medicine, Sakarya University, Sakarya, Turkey

Ali Fuat Erdem (AF)

Department of Anesthesiology and Intensive Care, Faculty of Medicine, Sakarya University, Sakarya, Turkey

Özlem Aydemir (Ö)

Department of Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Turkey

Ertuğrul Güçlü (E)

Department of Infectious Diseases, Faculty of Medicine, Sakarya University, Sakarya, Turkey

Yusuf Yürümez (Y)

Department of Emergency Medicine, Faculty of Medicine, Sakarya University, Sakarya, Turkey

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