Hyperpolarized


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
11 03 2021
Historique:
received: 10 07 2020
accepted: 28 02 2021
entrez: 12 3 2021
pubmed: 13 3 2021
medline: 15 12 2021
Statut: epublish

Résumé

Glioblastoma (GBM) is the most aggressive brain tumor type in adults. GBM is heterogeneous, with a compact core lesion surrounded by an invasive tumor front. This front is highly relevant for tumor recurrence but is generally non-detectable using standard imaging techniques. Recent studies demonstrated distinct metabolic profiles of the invasive phenotype in GBM. Magnetic resonance (MR) of hyperpolarized

Identifiants

pubmed: 33707647
doi: 10.1038/s41598-021-85339-7
pii: 10.1038/s41598-021-85339-7
pmc: PMC7952603
doi:

Substances chimiques

Carbon Isotopes 0
Aspartic Acid 30KYC7MIAI
Lactic Acid 33X04XA5AT
Pyruvic Acid 8558G7RUTR
N-acetylaspartate 997-55-7
Carbon-13 FDJ0A8596D
Glucose IY9XDZ35W2

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

5771

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Auteurs

Mor Mishkovsky (M)

Laboratory of Functional and Metabolic Imaging, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland. mor.mishkovsky@epfl.ch.

Olga Gusyatiner (O)

Neuroscience Research Center, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.
Service of Neurosurgery Lausanne, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.

Bernard Lanz (B)

Laboratory of Functional and Metabolic Imaging, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

Cristina Cudalbu (C)

Center for Biomedical Imaging (CIBM), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

Irene Vassallo (I)

Neuroscience Research Center, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.
Service of Neurosurgery Lausanne, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.

Marie-France Hamou (MF)

Neuroscience Research Center, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.
Service of Neurosurgery Lausanne, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.

Jocelyne Bloch (J)

Neuroscience Research Center, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.
Service of Neurosurgery Lausanne, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.

Arnaud Comment (A)

General Electric Healthcare, Chalfont St Giles, Buckinghamshire, HP8 4SP, UK.

Rolf Gruetter (R)

Laboratory of Functional and Metabolic Imaging, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Center for Biomedical Imaging (CIBM), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Department of Radiology, University of Geneva (UNIGE), Geneva, Switzerland.
Department of Radiology, University of Lausanne (UNIL), Lausanne, Switzerland.

Monika E Hegi (ME)

Neuroscience Research Center, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland. monika.hegi@chuv.ch.
Service of Neurosurgery Lausanne, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland. monika.hegi@chuv.ch.

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Classifications MeSH