Coexistence of three nevus lipomatosus cutaneus superficialis with typical, cutaneous adenolipoma-like, and dermal spindle cell lipoma-like histopathological features in a patient.
Adenoma
/ diagnosis
Adipocytes
/ pathology
Antigens, CD34
/ metabolism
Blood Vessels
/ pathology
Buttocks
/ pathology
Dermis
/ blood supply
Eccrine Glands
/ pathology
Female
Humans
Lipoma
/ diagnosis
Middle Aged
Neoplasms, Multiple Primary
/ pathology
Nevus
/ diagnosis
Skin Neoplasms
/ pathology
Thigh
/ pathology
CD34
coexistence
cutaneous adenolipoma
dermal spindle cell lipoma
nevus lipomatosus cutaneus superficialis
Journal
Journal of cutaneous pathology
ISSN: 1600-0560
Titre abrégé: J Cutan Pathol
Pays: United States
ID NLM: 0425124
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
revised:
03
03
2021
received:
29
12
2020
accepted:
08
03
2021
pubmed:
14
3
2021
medline:
27
11
2021
entrez:
13
3
2021
Statut:
ppublish
Résumé
We report an unique case of a patient who showed coexistence of three nevus lipomatosus cutaneus superficialis (NLCS) with typical, cutaneous adenolipoma (AL)-like, and dermal spindle cell lipoma (SCL)-like histopathological features. A 53-year-old woman presented with a 20-year history of skin-colored and slightly elevated nodules. These lesions were separately located on the lateral side (lesion 1) and medial side (lesion 2) of her left buttock and on her right thigh (lesion 3). Microscopically, all were ill-defined dermal lesions with some subcutaneous involvement and were mostly composed of mature adipocytes. The adipocytes formed small aggregates around blood vessels in the upper dermis. Lesions 1, 2, and 3 were diagnosed as NLCS, and additional features were recognized in lesions 2 and 3. Lesion 2 revealed eccrine glands and ducts amongst the lipomatous component, as seen in cutaneous AL. Lesion 3 had scattered CD34-positive spindle cells, which is representative of dermal SCL. These appearances were considered to be on the morphological spectrum of NLCS. In all three lesions, CD34-positive cells proliferated between the upper dermal blood vessels and their peripheral mature adipocytes. This pathological finding could be principal in NLCS and might be associated with its pathogenesis.
Substances chimiques
Antigens, CD34
0
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
961-964Informations de copyright
© 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
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