Inflammatory Determinants of Differential Tuberculosis Risk in Pre-Adolescent Children and Young Adults.

Adolescent Antigens, Bacterial / metabolism Child Cross-Sectional Studies Cytokines / metabolism Female Humans Inflammation / metabolism Inflammation Mediators / metabolism Male Mycobacterium tuberculosis / pathogenicity Tuberculosis / metabolism
age anti-mycobacterial immunity inflammation pediatric tuberculosis

Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2021
Historique:
received: 10 12 2020
accepted: 14 01 2021
entrez: 15 3 2021
pubmed: 16 3 2021
medline: 22 9 2021
Statut: epublish

Résumé

The risk of progression from

Identifiants

DOI: 10.3389/fimmu.2021.639965 PMID: 33717192 PMC: PMC7947716
pubmed: 33717192
doi: 10.3389/fimmu.2021.639965
pmc: PMC7947716
doi:

Substances chimiques

Antigens, Bacterial 0
Cytokines 0
Inflammation Mediators 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

639965

Informations de copyright

Copyright © 2021 Baguma, Mbandi, Rodo, Erasmus, Day, Makhethe, de Kock, van Rooyen, Stone, Bilek, Steyn, Africa, Darboe, Chegou, Tromp, Walzl, Hatherill, Penn-Nicholson and Scriba.

Déclaration de conflit d'intérêts

AP-N and TS have a patent of the RISK6 signature pending. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The handling editor declared a past co-authorship with several of the authors, TS and MH.

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Auteurs

Richard Baguma (R)

South African Tuberculosis Vaccine Initiative (SATVI), Department of Pathology, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, University of Cape Town, Cape Town, South Africa.

Stanley Kimbung Mbandi (SK)

South African Tuberculosis Vaccine Initiative (SATVI), Department of Pathology, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, University of Cape Town, Cape Town, South Africa.

Miguel J Rodo (MJ)

South African Tuberculosis Vaccine Initiative (SATVI), Department of Pathology, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, University of Cape Town, Cape Town, South Africa.

Mzwandile Erasmus (M)

South African Tuberculosis Vaccine Initiative (SATVI), Department of Pathology, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, University of Cape Town, Cape Town, South Africa.

Jonathan Day (J)

South African Tuberculosis Vaccine Initiative (SATVI), Department of Pathology, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, University of Cape Town, Cape Town, South Africa.

Lebohang Makhethe (L)

South African Tuberculosis Vaccine Initiative (SATVI), Department of Pathology, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, University of Cape Town, Cape Town, South Africa.

Marwou de Kock (M)

South African Tuberculosis Vaccine Initiative (SATVI), Department of Pathology, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, University of Cape Town, Cape Town, South Africa.

Michele van Rooyen (M)

South African Tuberculosis Vaccine Initiative (SATVI), Department of Pathology, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, University of Cape Town, Cape Town, South Africa.

Lynnett Stone (L)

South African Tuberculosis Vaccine Initiative (SATVI), Department of Pathology, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, University of Cape Town, Cape Town, South Africa.

Nicole Bilek (N)

South African Tuberculosis Vaccine Initiative (SATVI), Department of Pathology, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, University of Cape Town, Cape Town, South Africa.

Marcia Steyn (M)

South African Tuberculosis Vaccine Initiative (SATVI), Department of Pathology, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, University of Cape Town, Cape Town, South Africa.

Hadn Africa (H)

South African Tuberculosis Vaccine Initiative (SATVI), Department of Pathology, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, University of Cape Town, Cape Town, South Africa.

Fatoumatta Darboe (F)

South African Tuberculosis Vaccine Initiative (SATVI), Department of Pathology, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, University of Cape Town, Cape Town, South Africa.

Novel N Chegou (NN)

DST-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

Gerard Tromp (G)

DST-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

Gerhard Walzl (G)

DST-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

Mark Hatherill (M)

South African Tuberculosis Vaccine Initiative (SATVI), Department of Pathology, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, University of Cape Town, Cape Town, South Africa.

Adam Penn-Nicholson (A)

South African Tuberculosis Vaccine Initiative (SATVI), Department of Pathology, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, University of Cape Town, Cape Town, South Africa.

Thomas J Scriba (TJ)

South African Tuberculosis Vaccine Initiative (SATVI), Department of Pathology, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, University of Cape Town, Cape Town, South Africa.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adolescent › Inflammatory Determinants of Differential...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Antigènes bactériens › Inflammatory Determinants of Differential...
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Inflammatory Determinants of Differential...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études transversales › Inflammatory Determinants of Differential...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Inflammatory Determinants of Differential...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Inflammatory Determinants of Differential...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Inflammatory Determinants of Differential...
questionsmedicales.fr › Facteurs biologiques › Médiateurs de l'inflammation › Inflammatory Determinants of Differential...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Bâtonnets à Gram positif › Bâtonnets asporogènes à Gram positif › Bâtonnets asporogènes réguliers à Gram positif › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis › Inflammatory Determinants of Differential...
questionsmedicales.fr › Infection › Infections bactériennes et mycoses › Infections bactériennes › Infections bactériennes à Gram positif › Infections à Actinomycetales › Infections à Mycobacterium › Tuberculose › Inflammatory Determinants of Differential...