Extracorporeal cardiopulmonary resuscitation for severe chloroquine intoxication in a child - a case report.
Adolescent
Antimalarials
/ adverse effects
COVID-19
/ epidemiology
Cardiopulmonary Resuscitation
/ methods
Chloroquine
/ adverse effects
Extracorporeal Membrane Oxygenation
/ methods
Female
Heart Arrest
/ chemically induced
Humans
Pandemics
SARS-CoV-2
Severity of Illness Index
COVID-19 Drug Treatment
Arrhythmia
Emergency medicine
Extracorporeal Life support
Intensive Care
Pediatrics
Resuscitation
Journal
Scandinavian journal of trauma, resuscitation and emergency medicine
ISSN: 1757-7241
Titre abrégé: Scand J Trauma Resusc Emerg Med
Pays: England
ID NLM: 101477511
Informations de publication
Date de publication:
15 Mar 2021
15 Mar 2021
Historique:
received:
14
01
2021
accepted:
05
02
2021
entrez:
16
3
2021
pubmed:
17
3
2021
medline:
7
4
2021
Statut:
epublish
Résumé
Chloroquine use has increased worldwide recently in the setting of experimental treatment for the novel coronavirus disease (Covid-19). Nevertheless, in case of chloroquine intoxication, it can be life threatening, with cardiac arrest, due to its cardiac toxicity. This case study reports on a 14-years-old girl who presented in cardiac arrest after an uncommon suicide attempt by ingesting 3 g of chloroquine. After 66 min of cardio-pulmonary resuscitation (CPR), extracorporeal cardiopulmonary resuscitation (ECPR) was initiated, allowing cardiac function to recover. Chloroquine intoxication is a rare but serious condition due to its cardiac toxicity. Use of ECPR in this case of transient toxicity allowed a favorable evolution with little neurological impairment.
Sections du résumé
BACKGROUND
BACKGROUND
Chloroquine use has increased worldwide recently in the setting of experimental treatment for the novel coronavirus disease (Covid-19). Nevertheless, in case of chloroquine intoxication, it can be life threatening, with cardiac arrest, due to its cardiac toxicity.
CASE PRESENTATION
METHODS
This case study reports on a 14-years-old girl who presented in cardiac arrest after an uncommon suicide attempt by ingesting 3 g of chloroquine. After 66 min of cardio-pulmonary resuscitation (CPR), extracorporeal cardiopulmonary resuscitation (ECPR) was initiated, allowing cardiac function to recover.
CONCLUSIONS
CONCLUSIONS
Chloroquine intoxication is a rare but serious condition due to its cardiac toxicity. Use of ECPR in this case of transient toxicity allowed a favorable evolution with little neurological impairment.
Identifiants
pubmed: 33722251
doi: 10.1186/s13049-021-00850-0
pii: 10.1186/s13049-021-00850-0
pmc: PMC7958095
doi:
Substances chimiques
Antimalarials
0
Chloroquine
886U3H6UFF
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
48Références
Am J Emerg Med. 2001 Sep;19(5):420-4
pubmed: 11555803
Circulation. 2015 Nov 3;132(18 Suppl 2):S444-64
pubmed: 26472995
Anesth Analg. 2014 Jan;118(1):175-82
pubmed: 23749445
Circulation. 2016 Jan 12;133(2):165-76
pubmed: 26635402
Pediatr Crit Care Med. 2010 May;11(3):362-71
pubmed: 19924027
Clin Toxicol (Phila). 2015 Mar;53(3):145-50
pubmed: 25634667
Pediatrics. 2020 Jan;145(1):
pubmed: 31727859
Crit Care Med. 2000 Sep;28(9):3346-50
pubmed: 11009001
Resuscitation. 2004 Mar;60(3):343-6
pubmed: 15050768
Neth J Med. 2016 Jun;74(5):210-4
pubmed: 27323674
Resuscitation. 2016 Apr;101:12-20
pubmed: 26836946
Ann Acad Med Singap. 2011 Jun;40(6):296-7
pubmed: 21779619
Circulation. 2011 Nov 22;124(21):2329-37
pubmed: 22025603
Crit Care Med. 2008 May;36(5):1607-13
pubmed: 18434885
ASAIO J. 2017 Jul/Aug;63(4):456-463
pubmed: 28557863