Recurrent myocarditis in a patient with active ulcerative colitis: a case report and review of the literature.


Journal

BMJ open gastroenterology
ISSN: 2054-4774
Titre abrégé: BMJ Open Gastroenterol
Pays: England
ID NLM: 101660690

Informations de publication

Date de publication:
03 2021
Historique:
received: 17 12 2020
revised: 27 01 2021
accepted: 02 02 2021
entrez: 16 3 2021
pubmed: 17 3 2021
medline: 25 11 2021
Statut: ppublish

Résumé

Inflammatory bowel diseases such as ulcerative colitis (UC) may be complicated by several extraintestinal manifestations. These involve joints, skin, eyes and less commonly lungs and heart. Myocarditis may result from the toxic effect of drugs (ie, mesalazine) commonly used for the treatment of UC or due to infections (eg, Coxsackieviruses, enteroviruses, adenovirus). Here, we report a case of a 26-year old man affected by UC and complicated by two episodes of myocarditis. Both episodes occurred during two severe exacerbations of UC. However, in both cases the aetiology of myocarditis remains uncertain being ascribable to extraintestinal manifestation, drug toxicity or both.

Identifiants

pubmed: 33722804
pii: bmjgast-2020-000587
doi: 10.1136/bmjgast-2020-000587
pmc: PMC7970288
pii:
doi:

Substances chimiques

Mesalamine 4Q81I59GXC

Types de publication

Case Reports Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Giacomo Caio (G)

Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
Mucosal Immunology and Biology Research Center, Harvard Medical School, Boston, Massachusetts, USA.

Lisa Lungaro (L)

Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
Department of Internal Medicine, SS. Annunziata Hospital, Cento, University of Ferrara, Ferrara, Italy.

Fabio Caputo (F)

Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
Department of Internal Medicine, SS. Annunziata Hospital, Cento, University of Ferrara, Ferrara, Italy.

Maria Muccinelli (M)

Department of Internal Medicine, SS. Annunziata Hospital, Cento, University of Ferrara, Ferrara, Italy.

Maria Caterina Marcello (MC)

Department of Internal Medicine, SS. Annunziata Hospital, Cento, University of Ferrara, Ferrara, Italy.

Eleonora Zoli (E)

Department of Internal Medicine, SS. Annunziata Hospital, Cento, University of Ferrara, Ferrara, Italy.

Umberto Volta (U)

Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.

Roberto De Giorgio (R)

Department of Translational Medicine, University of Ferrara, Ferrara, Italy.

Giorgio Zoli (G)

Department of Translational Medicine, University of Ferrara, Ferrara, Italy giorgio.zoli@unife.it.
Department of Internal Medicine, SS. Annunziata Hospital, Cento, University of Ferrara, Ferrara, Italy.

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