Preface to the Special Issue "Presynaptic Dysfunction and Disease".

JNeurochem Special issue “Presynaptic Dysfunction and Disease” calcium neurodegeneration neurodevelopmental disorder neurotransmitter presynapse synaptic vesicle

Journal

Journal of neurochemistry
ISSN: 1471-4159
Titre abrégé: J Neurochem
Pays: England
ID NLM: 2985190R

Informations de publication

Date de publication:
04 2021
Historique:
received: 05 02 2021
accepted: 08 02 2021
pubmed: 18 3 2021
medline: 22 6 2021
entrez: 17 3 2021
Statut: ppublish

Résumé

The synapse is formed between a presynapse (which releases neurotransmitter) and the postsynapse (which transduces this chemical signal). Over the past decade, presynaptic dysfunction has emerged as a key mediator of a series of neurodevelopmental and neurodegenerative disorders. This special issue will highlight some of the important presynaptic molecules and mechanisms that are disrupted in these conditions and reveal potential routes for therapy.

Identifiants

pubmed: 33728654
doi: 10.1111/jnc.15319
doi:

Substances chimiques

Neurotransmitter Agents 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

102-106

Subventions

Organisme : CHDI Foundation
ID : A-14021
Organisme : National Health and Medical Research Council
ID : GNT2003710
Organisme : Wellcome Trust
ID : 204954/Z/16/Z
Pays : United Kingdom

Informations de copyright

© 2021 International Society for Neurochemistry.

Références

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Auteurs

Karen J Smillie (KJ)

Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, Scotland.
Muir Maxwell Epilepsy Centre, University of Edinburgh, Edinburgh, Scotland.

Michael A Cousin (MA)

Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, Scotland.
Muir Maxwell Epilepsy Centre, University of Edinburgh, Edinburgh, Scotland.
Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, Scotland.

Sarah L Gordon (SL)

The Florey Institute of Neuroscience and Mental Health, Melbourne Dementia Research Centre, The University of Melbourne, Melbourne, Vic., Australia.

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