Bronchopulmonary dysplasia as a determinant of respiratory outcomes in adult life.
adult lung function
bronchopulmonary dysplasia
dysanapsis
Journal
Pediatric pulmonology
ISSN: 1099-0496
Titre abrégé: Pediatr Pulmonol
Pays: United States
ID NLM: 8510590
Informations de publication
Date de publication:
11 2021
11 2021
Historique:
revised:
05
01
2021
received:
31
10
2020
accepted:
22
01
2021
pubmed:
18
3
2021
medline:
24
12
2021
entrez:
17
3
2021
Statut:
ppublish
Résumé
Respiratory disease is unfortunately common in preterm infants with the archetype being bronchopulmonary dysplasia (BPD). BPD affects approximately 50,000 preterm infants in the U.S. annually with substantial morbidity and mortality related to its pathology (alveolar, airway, and pulmonary vasculature maldevelopment). Predicting the likelihood and severity of chronic respiratory disease in these children as they age is difficult and compounded by the lack of consistent phenotyping. Barriers to understanding the actual scope of this problem include few longitudinal studies, information limited by small retrospective studies and the ever-changing landscape of therapies in the NICU that affect long-term respiratory outcomes. Thus, the true burden of adult respiratory disease caused by premature birth is currently unknown. Nevertheless, limited data suggest that a substantial percentage of children with a history of BPD have long-term respiratory symptoms and persistent airflow obstruction associated with altered lung function trajectories into adult life. Small airway disease with variable bronchodilator responsiveness, is the most common manifestation of lung dysfunction in adults with a history of BPD. The etiology of this is unclear however, developmental dysanapsis may underlie the airflow obstruction in some adults with a history of BPD. This type of flow limitation resembles that of aging adults with chronic obstructive lung disease with no history of smoking. It is also unclear whether lung function abnormalities in people with a history of BPD are static or if these individuals with BPD have a more accelerated decline in lung function as they age compared to controls. While some of the more significant mediators of lung function, such as tobacco smoke and respiratory infections have been identified, more work is necessary to identify the best means of preserving lung function for individuals born prematurely throughout their lifespan.
Identifiants
pubmed: 33730436
doi: 10.1002/ppul.25301
pmc: PMC8446084
mid: NIHMS1674344
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
3464-3471Subventions
Organisme : NIEHS NIH HHS
ID : P30 ES013508
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL114800
Pays : United States
Informations de copyright
© 2021 Wiley Periodicals LLC.
Références
Ann Am Thorac Soc. 2018 May;15(5):530-538
pubmed: 29328889
Pediatr Pulmonol. 2005 Nov;40(5):431-6
pubmed: 16161085
J Pediatr. 2020 Jul;222:85-90.e2
pubmed: 32417083
J Appl Physiol Respir Environ Exerc Physiol. 1983 May;54(5):1236-41
pubmed: 6863082
COPD. 2018 Jun-Aug;15(4):392-404
pubmed: 30064276
Allergy. 2009 Sep;64(9):1359-65
pubmed: 19416146
Pediatrics. 2016 Dec;138(6):
pubmed: 27940717
Braz J Otorhinolaryngol. 2017 Mar - Apr;83(2):207-214
pubmed: 27256033
Eur Respir J. 2019 Apr 4;53(4):
pubmed: 30765504
J Pediatr. 2017 Feb;181:12-28.e1
pubmed: 27908648
Lancet Respir Med. 2019 Apr;7(4):358-364
pubmed: 30765254
Pediatr Infect Dis J. 1997 Jan;16(1):18-23
pubmed: 9002095
Thorax. 2019 Dec;74(12):1147-1153
pubmed: 31558625
Thorax. 2013 Aug;68(8):760-6
pubmed: 23604458
PLoS Med. 2014 Jan 28;11(1):e1001596
pubmed: 24492409
N Engl J Med. 1967 Feb 16;276(7):357-68
pubmed: 5334613
Ann Am Thorac Soc. 2017 Jun 16;14(9):
pubmed: 28622012
Eur Respir J. 2008 Aug;32(2):321-8
pubmed: 18385172
Proc Am Thorac Soc. 2009 Dec;6(8):707-11
pubmed: 20008881
Am J Respir Crit Care Med. 2020 Jun 1;201(11):1398-1406
pubmed: 31995403
Laryngoscope. 2013 Nov;123(11):2735-41
pubmed: 23918048
J Allergy Clin Immunol. 2006 Oct;118(4):823-30
pubmed: 17030233
Paediatr Respir Rev. 2019 Nov;32:91-97
pubmed: 30745153
J Asthma Allergy. 2020 Oct 29;13:533-543
pubmed: 33149625
Pediatrics. 2010 Oct;126(4):632-7
pubmed: 20876173
Ann Am Thorac Soc. 2014 May;11(4):537-45
pubmed: 24502400
Lancet Respir Med. 2018 Jul;6(7):535-544
pubmed: 29628376
J Pediatr. 1986 Dec;109(6):1040-6
pubmed: 3783328
J Pediatr. 2015 Mar;166(3):531-7.e13
pubmed: 25449221
Pediatr Pulmonol. 2020 Feb;55(2):369-375
pubmed: 31804768
Thorax. 2017 Aug;72(8):702-711
pubmed: 28119488
Am J Respir Crit Care Med. 2011 Nov 15;184(10):1164-70
pubmed: 21836138
Am J Respir Crit Care Med. 2017 Aug 1;196(3):364-374
pubmed: 28249118
Pediatr Pulmonol. 2019 May;54(5):595-601
pubmed: 30694610
Am J Respir Crit Care Med. 2016 Apr 1;193(7):767-71
pubmed: 26566056
Respir Res. 2019 Feb 14;20(1):33
pubmed: 30764884
Arch Dis Child Fetal Neonatal Ed. 2020 Sep;105(5):496-503
pubmed: 31907276
PLoS One. 2015 Feb 23;10(2):e0118344
pubmed: 25706869
Am J Respir Crit Care Med. 2016 Sep 1;194(5):607-12
pubmed: 27585385
Exp Physiol. 2018 Feb 1;103(2):261-275
pubmed: 29193495
Am J Perinatol. 2020 Sep;37(S 02):S26-S30
pubmed: 32772357
Ann Am Thorac Soc. 2016 Aug;13(8):1262-70
pubmed: 27222921
Int J Mol Sci. 2016 Nov 22;17(11):
pubmed: 27879677
Pediatrics. 2008 Sep;122(3):479-85
pubmed: 18762515
Ann Am Thorac Soc. 2014 Dec;11(10):1528-37
pubmed: 25380058
Am J Respir Crit Care Med. 2001 Jun;163(7):1723-9
pubmed: 11401896
AJR Am J Roentgenol. 2000 May;174(5):1323-6
pubmed: 10789786
Pediatrics. 2006 Jun;117(6):1901-6
pubmed: 16740829
Semin Neonatol. 2003 Feb;8(1):73-81
pubmed: 12667832
JAMA. 2020 Jun 9;323(22):2268-2280
pubmed: 32515814
Am J Respir Crit Care Med. 2012 Apr 15;185(8):805-16
pubmed: 22135346
Lancet Respir Med. 2020 Aug;8(8):795-806
pubmed: 32763206
Genome Biol. 2007;8(10):R210
pubmed: 17916252
BMJ. 1991 Sep 21;303(6804):671-5
pubmed: 1912913
BMC Pediatr. 2015 Apr 10;15:37
pubmed: 25886363
Pediatrics. 2010 Sep;126(3):443-56
pubmed: 20732945
Front Pediatr. 2019 Dec 11;7:499
pubmed: 31921716
J Asthma Allergy. 2020 Sep 18;13:343-353
pubmed: 32982322
N Engl J Med. 2016 Sep 1;375(9):871-8
pubmed: 27579637
Am Rev Respir Dis. 1980 Feb;121(2):339-42
pubmed: 7362140
Clin Perinatol. 2018 Dec;45(4):787-804
pubmed: 30396418
Am J Respir Crit Care Med. 2017 Jan 1;195(1):96-103
pubmed: 27331632
Public Health Nutr. 2021 Apr;24(5):1009-1020
pubmed: 32327006
Pediatrics. 2012 Jan;129(1):e60-7
pubmed: 22201153
Pediatrics. 2014 Aug;134(2):415-20
pubmed: 25070315
Am J Respir Crit Care Med. 2013 May 15;187(10):1104-9
pubmed: 23491406
Pediatrics. 2015 Apr;135(4):607-16
pubmed: 25733757
Int J Chron Obstruct Pulmon Dis. 2010 Jun 03;5:153-64
pubmed: 20631815
N Engl J Med. 1986 Sep 25;315(13):785-90
pubmed: 3528853
Eur Radiol. 2009 Jul;19(7):1669-78
pubmed: 19205703
Am J Respir Cell Mol Biol. 2015 Mar;52(3):323-31
pubmed: 25068533
J Allergy Clin Immunol. 2012 Aug;130(2):299-307
pubmed: 22738675
BMC Public Health. 2015 Dec 01;15:1202
pubmed: 26627181
Lancet Respir Med. 2020 Nov;8(11):1081-1093
pubmed: 32598906
J Biol Chem. 2018 Jul 27;293(30):11772-11783
pubmed: 29866884
Pediatrics. 2015 Mar;135(3):e678-86
pubmed: 25647675
J Allergy Clin Immunol. 2017 Feb;139(2):379-386
pubmed: 28183432
Paediatr Respir Rev. 2018 Jun;27:74-85
pubmed: 29336933
Pediatr Pulmonol. 2017 Dec;52(12):1583-1591
pubmed: 29064170
Thorax. 2016 Nov;71(11):1012-1019
pubmed: 27259338
Chest. 2011 Nov;140(5):1162-1168
pubmed: 21868463
Am J Respir Crit Care Med. 2006 Apr 15;173(8):890-6
pubmed: 16456146
Pediatr Pulmonol. 2017 Jun;52(6):779-786
pubmed: 28125159
Thorax. 1982 Aug;37(8):564-71
pubmed: 7179184
JAMA. 2015 Sep 8;314(10):1039-51
pubmed: 26348753
N Engl J Med. 2007 Nov 8;357(19):1946-55
pubmed: 17989387
Nat Cell Biol. 2020 Nov;22(11):1295-1306
pubmed: 33046884
Lancet Respir Med. 2020 Jan;8(1):34-44
pubmed: 31606435
Ann Am Thorac Soc. 2014 Dec;11(10):1606-7
pubmed: 25549025
Pediatrics. 2013 Aug;132(2):290-7
pubmed: 23897914
Am J Respir Cell Mol Biol. 2015 Jul;53(1):60-73
pubmed: 25387348
Am J Respir Crit Care Med. 2017 Jul 1;196(1):39-46
pubmed: 28146643
Am J Respir Crit Care Med. 2008 May 15;177(10):1103-10
pubmed: 18292469