Social networks strongly predict the gut microbiota of wild mice.
Journal
The ISME journal
ISSN: 1751-7370
Titre abrégé: ISME J
Pays: England
ID NLM: 101301086
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
received:
24
09
2020
accepted:
19
02
2021
revised:
02
02
2021
pubmed:
19
3
2021
medline:
23
9
2021
entrez:
18
3
2021
Statut:
ppublish
Résumé
The mammalian gut teems with microbes, yet how hosts acquire these symbionts remains poorly understood. Research in primates suggests that microbes can be picked up via social contact, but the role of social interactions in non-group-living species remains underexplored. Here, we use a passive tracking system to collect high resolution spatiotemporal activity data from wild mice (Apodemus sylvaticus). Social network analysis revealed social association strength to be the strongest predictor of microbiota similarity among individuals, controlling for factors including spatial proximity and kinship, which had far smaller or nonsignificant effects. This social effect was limited to interactions involving males (male-male and male-female), implicating sex-dependent behaviours as driving processes. Social network position also predicted microbiota richness, with well-connected individuals having the most diverse microbiotas. Overall, these findings suggest social contact provides a key transmission pathway for gut symbionts even in relatively asocial mammals, that strongly shapes the adult gut microbiota. This work underlines the potential for individuals to pick up beneficial symbionts as well as pathogens from social interactions.
Identifiants
pubmed: 33731838
doi: 10.1038/s41396-021-00949-3
pii: 10.1038/s41396-021-00949-3
pmc: PMC8397773
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2601-2613Subventions
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/S009752/1
Pays : United Kingdom
Informations de copyright
© 2021. The Author(s).
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