Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis.
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
received:
30
06
2020
accepted:
04
03
2021
pubmed:
19
3
2021
medline:
3
8
2021
entrez:
18
3
2021
Statut:
ppublish
Résumé
The mammalian body plan is established shortly after the embryo implants into the maternal uterus, and our understanding of post-implantation developmental processes remains limited. Although pre- and peri-implantation mouse embryos are routinely cultured in vitro
Identifiants
pubmed: 33731940
doi: 10.1038/s41586-021-03416-3
pii: 10.1038/s41586-021-03416-3
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
119-124Subventions
Organisme : European Research Council
Pays : International
Références
Bedzhov, I. & Zernicka-Goetz, M. Self-organizing properties of mouse pluripotent cells initiate morphogenesis upon implantation. Cell 156, 1032–1044 (2014).
doi: 10.1016/j.cell.2014.01.023
White, M. D. et al. Long-lived binding of Sox2 to DNA predicts cell fate in the four-cell mouse embryo. Cell 165, 75–87 (2016).
doi: 10.1016/j.cell.2016.02.032
New, D. A. T. Whole-embryo culture and the study of mammalian embryos during organogenesis. Biol. Rev. Camb. Philos. Soc. 53, 81–122 (1978).
doi: 10.1111/j.1469-185X.1978.tb00993.x
Huang, Q. et al. Intravital imaging of mouse embryos. Science 368, 181–186 (2020).
doi: 10.1126/science.aba0210
Nicholas, J. S. & Rudnick, D. The development of rat embryos in tissue culture. Proc. Natl Acad. Sci. USA 20, 656–658 (1934).
doi: 10.1073/pnas.20.12.656
New, D. A. T. & Stein, K. F. Cultivation of mouse embryos in vitro. Nature 199, 297–299 (1963).
doi: 10.1038/199297a0
New, D. A. T., Coppola, P. T. & Terry, S. Culture of explanted rat embryos in rotating tubes. J. Reprod. Fertil. 35, 135–138 (1973).
doi: 10.1530/jrf.0.0350135
New, D. A. T. Development of explanted rat embryos in circulating medium. Development 17, 513–525 (1967).
doi: 10.1242/dev.17.3.513
Beddington, R. S. Induction of a second neural axis by the mouse node. Development 120, 613–620 (1994).
doi: 10.1242/dev.120.3.613
Parameswaran, M. & Tam, P. P. L. Regionalisation of cell fate and morphogenetic movement of the mesoderm during mouse gastrulation. Dev. Genet. 17, 16–28 (1995).
doi: 10.1002/dvg.1020170104
Tam, P. P. Postimplantation mouse development: whole embryo culture and micro-manipulation. Int. J. Dev. Biol. 42, 895–902 (1998).
pubmed: 9853819
Cantor, J. R. et al. Physiologic medium rewires cellular metabolism and reveals uric acid as an endogenous inhibitor of UMP synthase. Cell 169, 258–272 (2017).
doi: 10.1016/j.cell.2017.03.023
Nagamatsu, G., Shimamoto, S., Hamazaki, N., Nishimura, Y. & Hayashi, K. Mechanical stress accompanied with nuclear rotation is involved in the dormant state of mouse oocytes. Sci. Adv. 5, eaav9960 (2019).
doi: 10.1126/sciadv.aav9960
Ueda, Y. et al. Intrauterine pressures adjusted by Reichert’s membrane are crucial for early mouse morphogenesis. Cell Rep. 31, 107637 (2020).
doi: 10.1016/j.celrep.2020.107637
Downs, K. M. & Davies, T. Staging of gastrulating mouse embryos by morphological landmarks in the dissecting microscope. Development 118, 1255–1266 (1993).
doi: 10.1242/dev.118.4.1255
van Maele-Fabry, G., Delhaise, F. & Picard, J. J. Evolution of the developmental scores of sixteen morphological features in mouse embryos displaying 0 to 30 somites. Int. J. Dev. Biol. 36, 161–167 (1992).
pubmed: 1627466
Stelzer, Y. et al. Parent-of-origin DNA methylation dynamics during mouse development. Cell Rep. 16, 3167–3180 (2016).
doi: 10.1016/j.celrep.2016.08.066
McDole, K. et al. In toto imaging and reconstruction of post-implantation mouse development at the single-cell level. Cell 175, 859–876 (2018).
doi: 10.1016/j.cell.2018.09.031
Ibarra-Soria, X. et al. Defining murine organogenesis at single-cell resolution reveals a role for the leukotriene pathway in regulating blood progenitor formation. Nat. Cell Biol. 20, 127–134 (2018).
doi: 10.1038/s41556-017-0013-z
Pijuan-Sala, B. et al. A single-cell molecular map of mouse gastrulation and early organogenesis. Nature 566, 490–495 (2019).
doi: 10.1038/s41586-019-0933-9
Cao, J. et al. The single-cell transcriptional landscape of mammalian organogenesis. Nature 566, 496–502 (2019).
doi: 10.1038/s41586-019-0969-x
Saito, T. & Nakatsuji, N. Efficient gene transfer into the embryonic mouse brain using in vivo electroporation. Dev. Biol. 240, 237–246 (2001).
doi: 10.1006/dbio.2001.0439
Beronja, S., Livshits, G., Williams, S. & Fuchs, E. Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos. Nat. Med. 16, 821–827 (2010).
doi: 10.1038/nm.2167
Morgani, S., Nichols, J. & Hadjantonakis, A. K. The many faces of pluripotency: in vitro adaptations of a continuum of in vivo states. BMC Dev. Biol. 17, 7 (2017).
doi: 10.1186/s12861-017-0150-4
Kojima, Y. et al. The transcriptional and functional properties of mouse epiblast stem cells resemble the anterior primitive streak. Cell Stem Cell 14, 107–120 (2014).
doi: 10.1016/j.stem.2013.09.014
Wu, J. et al. An alternative pluripotent state confers interspecies chimaeric competency. Nature 521, 316–321 (2015).
doi: 10.1038/nature14413
Huang, Y., Osorno, R., Tsakiridis, A. & Wilson, V. In vivo differentiation potential of epiblast stem cells revealed by chimeric embryo formation. Cell Rep. 2, 1571–1578 (2012).
doi: 10.1016/j.celrep.2012.10.022
van Wilgenburg, B., Browne, C., Vowles, J. & Cowley, S. A. Efficient, long term production of monocyte-derived macrophages from human pluripotent stem cells under partly-defined and fully-defined conditions. PLoS One 8, e71098 (2013).
doi: 10.1371/journal.pone.0071098
Gafni, O. et al. Derivation of novel human ground state naive pluripotent stem cells. Nature 504, 282–286 (2013).
doi: 10.1038/nature12745
Harrison, S. E., Sozen, B., Christodoulou, N., Kyprianou, C. & Zernicka-Goetz, M. Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro. Science 356, eaal1810 (2017).
doi: 10.1126/science.aal1810
Aguilera-Castrejon, A. & Hanna, J. H. Highly conducive ex utero mouse embryogenesis from pre-gastrulation to late organogenesis. Protoc. Exch. https://doi.org/10.21203/rs.3.pex-1372/v1 (2021).
Renier, N. et al. iDISCO: a simple, rapid method to immunolabel large tissue samples for volume imaging. Cell 159, 896–910 (2014).
doi: 10.1016/j.cell.2014.10.010
Stuart, T. et al. Comprehensive integration of single-cell data. Cell 177, 1888–1902 (2019).
doi: 10.1016/j.cell.2019.05.031
Butler, A., Hoffman, P., Smibert, P., Papalexi, E. & Satija, R. Integrating single-cell transcriptomic data across different conditions, technologies, and species. Nat. Biotechnol. 36, 411–420 (2018).
doi: 10.1038/nbt.4096
Aibar, S. et al. SCENIC: single-cell regulatory network inference and clustering. Nat. Methods 14, 1083–1086 (2017).
doi: 10.1038/nmeth.4463
Ritchie, M. E. et al. limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res. 43, e47 (2015).
doi: 10.1093/nar/gkv007