The role of LTBPs in TGF beta signaling.
LTBP
TGF beta
cell signaling
mouse mutants
Journal
Developmental dynamics : an official publication of the American Association of Anatomists
ISSN: 1097-0177
Titre abrégé: Dev Dyn
Pays: United States
ID NLM: 9201927
Informations de publication
Date de publication:
01 2022
01 2022
Historique:
revised:
25
02
2021
received:
08
01
2021
accepted:
13
03
2021
pubmed:
21
3
2021
medline:
8
4
2022
entrez:
20
3
2021
Statut:
ppublish
Résumé
The purpose of this review is to discuss the transforming growth factor beta (TGFB) binding proteins (LTBP) with respect to their participation in the activity of TGFB. We first describe pertinent aspects of the biology and cell function of the LTBPs. We then summarize the physiological consequences of LTBP loss in humans and mice. Finally, we consider a number of outstanding questions relating to LTBP function.
Substances chimiques
Latent TGF-beta Binding Proteins
0
Transforming Growth Factor beta
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
95-104Subventions
Organisme : NHLBI NIH HHS
ID : P01 HL134605
Pays : United States
Organisme : NHLBI NIH HHS
ID : 5 P01HL134605-03
Pays : United States
Informations de copyright
© 2021 American Association of Anatomists.
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