Persistent collective motion of a dispersing membrane domain.
Journal
Biophysical journal
ISSN: 1542-0086
Titre abrégé: Biophys J
Pays: United States
ID NLM: 0370626
Informations de publication
Date de publication:
18 05 2021
18 05 2021
Historique:
received:
04
01
2021
revised:
23
02
2021
accepted:
12
03
2021
pubmed:
22
3
2021
medline:
3
7
2021
entrez:
21
3
2021
Statut:
ppublish
Résumé
We study the Brownian motion of an assembly of mobile inclusions embedded in a fluid membrane. The motion includes the dispersal of the assembly, accompanied by the diffusion of its center of mass. Usually, the former process is much faster than the latter because the diffusion coefficient of the center of mass is inversely proportional to the number of particles. However, in the case of membrane inclusions, we find that the two processes occur on the same timescale, thus significantly prolonging the lifetime of the assembly as a collectively moving object. This effect is caused by the quasi-two-dimensional membrane flows, which couple the motions of even the most remote inclusions in the assembly. The same correlations also cause the diffusion coefficient of the center of mass to decay slowly with time, resulting in weak subdiffusion. We confirm our analytical results by Brownian dynamics simulations with flow-mediated correlations. The effect reported here should have implications for the stability of nanoscale membrane heterogeneities.
Identifiants
pubmed: 33744264
pii: S0006-3495(21)00240-X
doi: 10.1016/j.bpj.2021.03.011
pmc: PMC8204345
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2030-2039Informations de copyright
Copyright © 2021 Biophysical Society. Published by Elsevier Inc. All rights reserved.
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