Giant mantle cell lymphoma in the soft tissue of the leg: rare presentation.
Mantle cell lymphoma
giant mass
recurrence
soft tissue
Journal
Tumori
ISSN: 2038-2529
Titre abrégé: Tumori
Pays: United States
ID NLM: 0111356
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
pubmed:
23
3
2021
medline:
15
12
2021
entrez:
22
3
2021
Statut:
ppublish
Résumé
Mantle cell lymphomas are aggressive, mature B-cell neoplasms characteristically showing overexpression of cyclin D1. Although lymphadenopathy is the most common presentation, involvement of extranodal sites including bone marrow, peripheral blood, liver, gastrointestinal system, and Waldeyer ring is also seen frequently. Soft tissue localization is extremely rare. It has blastoid and pleomorphic subtypes associated with aggressive course. We describe a 74-year-old man who had been diagnosed 3 years previously with "mantle cell lymphoma-blastoid type" and presented 3 months ago with a giant mass in the right lower extremity that enlarged rapidly up to 15 cm in a few months. We present this rare presentation, which was evaluated in favor of hemangioma before biopsy, together with the data in the literature to emphasize the need for differential diagnosis, especially in cases with a clinical history.
Sections du résumé
BACKGROUND
BACKGROUND
Mantle cell lymphomas are aggressive, mature B-cell neoplasms characteristically showing overexpression of cyclin D1. Although lymphadenopathy is the most common presentation, involvement of extranodal sites including bone marrow, peripheral blood, liver, gastrointestinal system, and Waldeyer ring is also seen frequently. Soft tissue localization is extremely rare. It has blastoid and pleomorphic subtypes associated with aggressive course.
CASE DESCRIPTION
METHODS
We describe a 74-year-old man who had been diagnosed 3 years previously with "mantle cell lymphoma-blastoid type" and presented 3 months ago with a giant mass in the right lower extremity that enlarged rapidly up to 15 cm in a few months.
CONCLUSION
CONCLUSIONS
We present this rare presentation, which was evaluated in favor of hemangioma before biopsy, together with the data in the literature to emphasize the need for differential diagnosis, especially in cases with a clinical history.
Identifiants
pubmed: 33745393
doi: 10.1177/03008916211001925
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM