Retrospective review of diphenhydramine versus diphenhydramine plus glucocorticoid for treatment of uncomplicated allergic reaction in dogs.
Animals
Dexamethasone
/ administration & dosage
Diphenhydramine
/ administration & dosage
Dog Diseases
/ drug therapy
Dogs
Drug Therapy, Combination
Glucocorticoids
/ administration & dosage
Histamine H1 Antagonists
/ administration & dosage
Hypersensitivity
/ drug therapy
Male
Retrospective Studies
allergic reaction
canine
glucocorticoid
steroid
type I hypersensitivity reaction
Journal
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
ISSN: 1476-4431
Titre abrégé: J Vet Emerg Crit Care (San Antonio)
Pays: United States
ID NLM: 101152804
Informations de publication
Date de publication:
May 2021
May 2021
Historique:
revised:
17
06
2019
received:
16
01
2019
accepted:
23
06
2019
pubmed:
23
3
2021
medline:
24
6
2021
entrez:
22
3
2021
Statut:
ppublish
Résumé
To report the outcome of treatment of uncomplicated allergic reactions in dogs with diphenhydramine vs diphenhydramine plus glucocorticoid and to determine the incidence rate of uncomplicated allergic reactions DESIGN: Retrospective study between January 1, 2012 and August 15, 2018. Privately owned, 24-hour emergency and specialty referral veterinary hospital. Eight hundred and eighty cases of dogs treated for uncomplicated allergic reaction with diphenhydramine alone or in combination with a glucocorticoid. None. Two hundred ninety-nine dogs were treated with diphenhydramine alone, and 581 were treated with diphenhydramine plus Dex SP. There was no difference between the 2 groups for response to initial therapy, need for additional veterinary intervention after discharge, or persistent signs at follow-up. The cumulative incidence of emergency department presentation for uncomplicated allergic reaction in this hospital was 1.2%. There was no difference in measured outcomes between dogs treated with diphenhydramine alone vs those treated with a glucocorticoid in addition to diphenhydramine in this population of dogs.
Substances chimiques
Glucocorticoids
0
Histamine H1 Antagonists
0
dexamethasone 21-phosphate
2BP70L44PR
Dexamethasone
7S5I7G3JQL
Diphenhydramine
8GTS82S83M
Types de publication
Clinical Trial, Veterinary
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
380-386Informations de copyright
© Veterinary Emergency and Critical Care Society 2021.
Références
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