Brain Plasma Membrane Monoamine Transporter in Health and Disease.
5-HT
Autism
Brain
Catecholamine
Choroid plexus
Depression
MPP+
Monoamine neurotransmitter
OCT3
Organic cation
PMAT
Slc29a4 knockout
Uptake1
Uptake2
Journal
Handbook of experimental pharmacology
ISSN: 0171-2004
Titre abrégé: Handb Exp Pharmacol
Pays: Germany
ID NLM: 7902231
Informations de publication
Date de publication:
2021
2021
Historique:
pubmed:
23
3
2021
medline:
29
10
2021
entrez:
22
3
2021
Statut:
ppublish
Résumé
Precise control of monoamine neurotransmitter levels in the central nervous system (CNS) is crucial for proper brain function. Dysfunctional monoamine signaling is associated with several neuropsychiatric and neurodegenerative disorders. The plasma membrane monoamine transporter (PMAT) is a new polyspecific organic cation transporter encoded by the SLC29A4 gene. Capable of transporting monoamine neurotransmitters with low affinity and high capacity, PMAT represents a major uptake
Identifiants
pubmed: 33751232
doi: 10.1007/164_2021_446
doi:
Substances chimiques
Serotonin Plasma Membrane Transport Proteins
0
Serotonin
333DO1RDJY
Dopamine
VTD58H1Z2X
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
253-280Informations de copyright
© 2021. The Author(s), under exclusive license to Springer Nature Switzerland AG.
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