The characteristics of gastrointestinal symptoms in patients with severe COVID-19: a systematic review and meta-analysis.
Abdominal pain
COVID-19
Gastrointestinal system
Meta-analysis
Systematic review
Journal
Journal of gastroenterology
ISSN: 1435-5922
Titre abrégé: J Gastroenterol
Pays: Japan
ID NLM: 9430794
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
received:
29
01
2021
accepted:
08
03
2021
pubmed:
25
3
2021
medline:
4
5
2021
entrez:
24
3
2021
Statut:
ppublish
Résumé
Although primarily a respiratory illness, several studies have shown that COVID-19 causes elevation of liver enzymes and various gastrointestinal (GI) symptoms. The aim of this study was to undertake a systematic review and meta-analysis to determine whether the presence of gastrointestinal (GI) symptoms contributed toward COVID-19 severity, and identify the GI symptoms characteristic of severe COVID-19. We conducted a literature search of PubMed from December 1, 2019, to June 30, 2020, and identified all reports with GI symptoms reported. A meta-analysis comparing the severity of COVID-19 with the presence of liver enzyme elevation and GI symptoms was performed using RevMan version 5.4. Pooled data from 15,305 unique reverse transcriptase-polymerase chain reaction positive COVID-19 patients from 44 studies were analyzed. We found that the severe COVID-19 patients significantly had abdominal pain compared to the non-severe COVID-19 patients (OR = 2.70, 95% CI 1.17-6.27, Z = 2.32, p = 0.02, I
Identifiants
pubmed: 33759041
doi: 10.1007/s00535-021-01778-z
pii: 10.1007/s00535-021-01778-z
pmc: PMC7987120
doi:
Types de publication
Journal Article
Meta-Analysis
Research Support, Non-U.S. Gov't
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
409-420Subventions
Organisme : Japan Society for the Promotion of Science
ID : 19H03518
Organisme : Ministry of Health, Labour and Welfare
ID : Grants for research on intractable diseases investigation and Research for intractable Inflammatory Bowel Disease
Commentaires et corrections
Type : ErratumIn
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