Crystal and molecular structure of V-amylose complexed with ibuprofen.
Amylose
Crystal structure
Ibuprofen
Inclusion compound
Journal
Carbohydrate polymers
ISSN: 1879-1344
Titre abrégé: Carbohydr Polym
Pays: England
ID NLM: 8307156
Informations de publication
Date de publication:
01 Jun 2021
01 Jun 2021
Historique:
received:
06
12
2020
revised:
30
01
2021
accepted:
26
02
2021
entrez:
26
3
2021
pubmed:
27
3
2021
medline:
4
5
2021
Statut:
ppublish
Résumé
Rectangular V-amylose single crystals were prepared by adding racemic ibuprofen to hot dilute aqueous solutions of native and enzymatically-synthesized amylose. The lamellar thickness increased with increasing degree of polymerization of amylose and reached a plateau at about 7 nm, consistent with a chain-folding mechanism. The CP/MAS NMR spectrum as well as base-plane electron and powder X-ray diffraction patterns recorded from hydrated specimens were similar to those of V-amylose complexed with propan-2-ol. Amylose was crystallized in an orthorhombic unit cell with parameters a = 2.824 ± 0.001 nm, b = 2.966 ± 0.001 nm, and c = 0.800 ± 0.001 nm. A molecular model was proposed based on structural analogies with the V
Identifiants
pubmed: 33766372
pii: S0144-8617(21)00272-1
doi: 10.1016/j.carbpol.2021.117885
pii:
doi:
Substances chimiques
Nanoconjugates
0
Amylose
9005-82-7
Ibuprofen
WK2XYI10QM
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
117885Informations de copyright
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