Growth Hormone Releasing Hormone in Endothelial Barrier Function.
acute lung injury
acute respiratory distress syndrome
sepsis
Journal
Trends in endocrinology and metabolism: TEM
ISSN: 1879-3061
Titre abrégé: Trends Endocrinol Metab
Pays: United States
ID NLM: 9001516
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
received:
18
02
2021
revised:
25
02
2021
accepted:
01
03
2021
pubmed:
28
3
2021
medline:
1
3
2022
entrez:
27
3
2021
Statut:
ppublish
Résumé
Growth hormone releasing hormone (GHRH) is the integral regulator of the growth hormone (GH)-insulin-like growth factor 1 (IGF-1) axis. It exerts mitogenic effects in a plethora of progressive cancers. Recent evidence suggests the emerging role of that 44-amino acid (aa) neuropeptide in lung endothelial barrier function (EBF), which will be discussed herein.
Identifiants
pubmed: 33771415
pii: S1043-2760(21)00047-3
doi: 10.1016/j.tem.2021.03.001
pmc: PMC8102361
mid: NIHMS1692221
pii:
doi:
Substances chimiques
Human Growth Hormone
12629-01-5
Insulin-Like Growth Factor I
67763-96-6
Growth Hormone-Releasing Hormone
9034-39-3
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
338-340Subventions
Organisme : NIGMS NIH HHS
ID : P20 GM103424
Pays : United States
Informations de copyright
Copyright © 2021 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Interests The author declares no conflicts of interest.
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