A Molecular Lid Mechanism of K

Amino Acid Sequence Animals Binding Sites / drug effects Biophysics / methods Ion Channel Gating / drug effects Peptides / pharmacology Potassium / metabolism Potassium Channels / metabolism Scorpion Venoms / pharmacology Xenopus laevis / metabolism
channel cone toxin lid-block molecular-dynamics pore-collapse

Journal

Journal of molecular biology
ISSN: 1089-8638
Titre abrégé: J Mol Biol
Pays: Netherlands
ID NLM: 2985088R

Informations de publication

Date de publication:
20 08 2021
Historique:
received: 04 11 2020
revised: 08 03 2021
accepted: 16 03 2021
pubmed: 28 3 2021
medline: 21 10 2021
entrez: 27 3 2021
Statut: ppublish

Résumé

Many venomous organisms carry in their arsenal short polypeptides that block K

Identifiants

DOI: 10.1016/j.jmb.2021.166957 PMID: 33771569
pubmed: 33771569
pii: S0022-2836(21)00158-3
doi: 10.1016/j.jmb.2021.166957
pii:
doi:

Substances chimiques

Peptides 0
Potassium Channels 0
Scorpion Venoms 0
Potassium RWP5GA015D

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

166957

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Auteurs

Chandamita Saikia (C)

Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 76100, Israel.

Orly Dym (O)

Structural Proteomic Unit, Weizmann Institute of Science, Rehovot 76100, Israel.

Hagit Altman-Gueta (H)

Department of Plant Molecular Biology and Ecology, Tel-Aviv University, Tel-Aviv 69978, Israel.

Dalia Gordon (D)

Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 76100, Israel.

Eitan Reuveny (E)

Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 76100, Israel. Electronic address: e.reuveny@weizmann.ac.il.

Izhar Karbat (I)

Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 76100, Israel. Electronic address: izhar.karbat@weizmann.ac.il.

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Classifications MeSH

questionsmedicales.fr › Sciences de l'information › Sources d'information › Services d'information › Documentation › Données de séquences moléculaires › Séquence d'acides aminés › A Molecular Lid Mechanism of K
questionsmedicales.fr › Eucaryotes › Animaux › A Molecular Lid Mechanism of K
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Sites de fixation › A Molecular Lid Mechanism of K
questionsmedicales.fr › Disciplines des sciences naturelles › Physique › Biophysique › A Molecular Lid Mechanism of K
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes électrophysiologiques › Ouverture et fermeture des portes des canaux ioniques › A Molecular Lid Mechanism of K
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › A Molecular Lid Mechanism of K
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux légers › Potassium › A Molecular Lid Mechanism of K
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux potassiques › A Molecular Lid Mechanism of K
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Venins › Venins d'arthropode › Venins de scorpion › A Molecular Lid Mechanism of K
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Amphibiens › Anura › Pipidae › Xenopus › Xenopus laevis › A Molecular Lid Mechanism of K