Impact of the COVID-19 pandemic on liver donation and transplantation: A review of the literature.
COVID-19
/ diagnosis
Disease Transmission, Infectious
/ prevention & control
Graft vs Host Disease
/ prevention & control
Health Care Rationing
Humans
Immunosuppressive Agents
/ therapeutic use
Liver Transplantation
/ trends
Mass Screening
SARS-CoV-2
Tissue and Organ Procurement
/ trends
Transplants
/ virology
Donor and recipient screening
Donor-to-recipient transmission
Immunosuppression
Liver cirrhosis
Resource allocation in transplantation
Severe acute respiratory syndrome coronavirus type 2
Journal
World journal of gastroenterology
ISSN: 2219-2840
Titre abrégé: World J Gastroenterol
Pays: United States
ID NLM: 100883448
Informations de publication
Date de publication:
14 Mar 2021
14 Mar 2021
Historique:
received:
11
01
2021
revised:
01
02
2021
accepted:
25
02
2021
entrez:
29
3
2021
pubmed:
30
3
2021
medline:
2
4
2021
Statut:
ppublish
Résumé
The coronavirus disease 2019 (COVID-19) pandemic has upended healthcare systems worldwide and led to an inevitable decrease in liver transplantation (LT) activity. During the first pandemic wave, administrators and clinicians were obliged to make the difficult decision of whether to suspend or continue a life-saving procedure based on the scarce available evidence regarding the risk of transmission and mortality in immunosuppressed patients. Those centers where the activity continued or was heavily restricted were obliged to screen donors and recipients, design COVID-safe clinical pathways, and promote telehealth to prevent nosocomial transmission. Despite the ever-growing literature on COVID-19, the amount of high-quality literature on LT remains limited. This review will provide an updated view of the impact of the pandemic on LT programs worldwide. Donor and recipient screening, strategies for waitlist prioritization, and posttransplant risk of infection and mortality are discussed. Moreover, a particular focus is given to the possibility of donor-to-recipient transmission and immunosuppression management in COVID-positive recipients.
Identifiants
pubmed: 33776364
doi: 10.3748/wjg.v27.i10.928
pmc: PMC7968133
doi:
Substances chimiques
Immunosuppressive Agents
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
928-938Informations de copyright
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflict-of-interest statement: The authors declare no conflict of interests for this article.
Références
PLoS One. 2017 Mar 20;12(3):e0174173
pubmed: 28319169
Am J Transplant. 2020 Jul;20(7):1787-1794
pubmed: 32400087
Hepatology. 2021 Feb;73(2):868-869
pubmed: 32654313
J Hepatol. 2020 Oct;73(4):873-881
pubmed: 32454041
Lancet. 2020 May 23;395(10237):e95-e96
pubmed: 32407668
Liver Transpl. 2020 Aug;26(8):1052-1055
pubmed: 32369251
Crit Care Resusc. 2020 Apr 15;22(2):95-97
pubmed: 32294809
Transpl Int. 2020 Aug;33(8):969-970
pubmed: 32348586
J Infect. 2021 Mar;82(3):414-451
pubmed: 33127455
Transplant Proc. 2020 Nov;52(9):2707-2710
pubmed: 32800515
J Hepatol. 2020 Oct;73(4):807-816
pubmed: 32437830
Transpl Int. 2020 Dec;33(12):1825-1826
pubmed: 33037657
Transpl Infect Dis. 2020 Oct;22(5):e13384
pubmed: 32574408
Am J Transplant. 2020 Jul;20(7):1795-1799
pubmed: 32368850
J Hepatol. 2020 Nov;73(5):1063-1071
pubmed: 32526252
Clin Gastroenterol Hepatol. 2020 Aug;18(9):2131-2133.e1
pubmed: 32334081
Clin Infect Dis. 2020 Dec 14;:
pubmed: 33315049
J Hepatol. 2021 Jan;74(1):148-155
pubmed: 32750442
Gut. 2020 Oct;69(10):1832-1840
pubmed: 32571972
Transplantation. 2021 Jan 1;105(1):14-17
pubmed: 33141806
Transplantation. 2021 Jan 1;105(1):29-36
pubmed: 33165237
Am J Transplant. 2020 Jul;20(7):1780-1784
pubmed: 32243677
Clin Res Hepatol Gastroenterol. 2020 Aug 7;:101512
pubmed: 32859555
Nat Rev Gastroenterol Hepatol. 2020 Sep;17(9):526-528
pubmed: 32651555
Am J Transplant. 2020 Nov;20(11):3042-3050
pubmed: 32515125
Hepatology. 2020 Oct;72(4):1491-1493
pubmed: 32220017
Hepatology. 2020 Jul;72(1):287-304
pubmed: 32298473
Gut. 2020 Aug 18;:
pubmed: 32816964
Arch Pathol Lab Med. 2020 Apr 17;:
pubmed: 32302212
Clin Res Hepatol Gastroenterol. 2020 Sep;44(4):e81-e83
pubmed: 32646848
Ann Surg. 2020 Jun 2;:
pubmed: 32487802
J Infect Public Health. 2020 Nov;13(11):1678-1679
pubmed: 32405329
Hepatol Commun. 2020 Sep 29;:
pubmed: 33043228
Liver Transpl. 2020 Jun;26(6):832-834
pubmed: 32196933
Lancet Gastroenterol Hepatol. 2020 Aug;5(8):724-725
pubmed: 32505228
Transpl Int. 2020 Oct;33(10):1244-1252
pubmed: 32609908
Hepatol Int. 2020 Jul;14(4):415-428
pubmed: 32447721
Am J Transplant. 2020 Jul;20(7):1809-1818
pubmed: 32282982
Lancet Gastroenterol Hepatol. 2020 Nov;5(11):1008-1016
pubmed: 32866433
Transplant Proc. 2020 Nov;52(9):2601-2606
pubmed: 32586665
Am J Transplant. 2020 Nov;20(11):3261-3262
pubmed: 32502313
Transplant Direct. 2020 Oct 08;6(11):e611
pubmed: 33134487
Clin Res Hepatol Gastroenterol. 2020 Nov 8;:101560
pubmed: 33176991
Transpl Infect Dis. 2020 Oct;22(5):e13353
pubmed: 32500942
Hepatology. 2020 Dec;72(6):1900-1911
pubmed: 32964510
Gastroenterology. 2021 Mar;160(4):1151-1163.e3
pubmed: 33307029
Lancet Gastroenterol Hepatol. 2020 Jun;5(6):532-533
pubmed: 32278366
Liver Transpl. 2020 Dec;26(12):1665-1666
pubmed: 33021025
Transpl Infect Dis. 2021 Feb;23(1):e13421
pubmed: 32779808
Am J Transplant. 2020 Oct;20(10):2938-2941
pubmed: 32400013
JHEP Rep. 2020 Oct;2(5):100169
pubmed: 32835190
Am J Transplant. 2020 Jul;20(7):1773-1779
pubmed: 32202064
Nature. 2018 May;557(7703):50-56
pubmed: 29670285
Am J Transplant. 2020 Nov;20(11):2997-3007
pubmed: 32515544
Scientometrics. 2020 Aug 5;:1-4
pubmed: 32836531
JAMA. 2020 May 12;323(18):1843-1844
pubmed: 32159775
Dig Liver Dis. 2021 Feb;53(2):169-170
pubmed: 32921600