The First Episode Rapid Early Intervention for Eating Disorders - Upscaled study: Clinical outcomes.


Journal

Early intervention in psychiatry
ISSN: 1751-7893
Titre abrégé: Early Interv Psychiatry
Pays: Australia
ID NLM: 101320027

Informations de publication

Date de publication:
01 2022
Historique:
revised: 02 03 2021
received: 10 10 2020
accepted: 06 03 2021
pubmed: 30 3 2021
medline: 11 3 2022
entrez: 29 3 2021
Statut: ppublish

Résumé

First Episode Rapid Early Intervention for Eating Disorders (FREED) is a service model and care pathway for emerging adults aged 16 to 25-years with a recent onset eating disorder (ED) of <3 years. A previous single-site study suggests that FREED significantly improves clinical outcomes compared to treatment-as-usual (TAU). The present study (FREED-Up) assessed the scalability of FREED. A multi-centre quasi-experimental pre-post design was used, comparing patient outcomes before and after implementation of FREED in participating services. FREED patients (n = 278) were consecutive, prospectively ascertained referrals to four specialist ED services in England, assessed at four time points over 12 months on ED symptoms, mood, service utilization and cost. FREED patients were compared to a TAU cohort (n = 224) of similar patients, identified retrospectively from electronic patient records in participating services. All were emerging adults aged 16-25 experiencing a first episode ED of <3 years duration. Overall, FREED patients made significant and rapid clinical improvements over time. 53.2% of FREED patients with anorexia nervosa reached a healthy weight at the 12-month timepoint, compared to only 17.9% of TAU patients (X FREED is robust and scalable and is associated with substantial improvements in clinical outcomes, reduction in inpatient or day-patient admissions, and cost-savings.

Sections du résumé

BACKGROUND
First Episode Rapid Early Intervention for Eating Disorders (FREED) is a service model and care pathway for emerging adults aged 16 to 25-years with a recent onset eating disorder (ED) of <3 years. A previous single-site study suggests that FREED significantly improves clinical outcomes compared to treatment-as-usual (TAU). The present study (FREED-Up) assessed the scalability of FREED. A multi-centre quasi-experimental pre-post design was used, comparing patient outcomes before and after implementation of FREED in participating services.
METHODS
FREED patients (n = 278) were consecutive, prospectively ascertained referrals to four specialist ED services in England, assessed at four time points over 12 months on ED symptoms, mood, service utilization and cost. FREED patients were compared to a TAU cohort (n = 224) of similar patients, identified retrospectively from electronic patient records in participating services. All were emerging adults aged 16-25 experiencing a first episode ED of <3 years duration.
RESULTS
Overall, FREED patients made significant and rapid clinical improvements over time. 53.2% of FREED patients with anorexia nervosa reached a healthy weight at the 12-month timepoint, compared to only 17.9% of TAU patients (X
DISCUSSION
FREED is robust and scalable and is associated with substantial improvements in clinical outcomes, reduction in inpatient or day-patient admissions, and cost-savings.

Identifiants

pubmed: 33781000
doi: 10.1111/eip.13139
pmc: PMC9291113
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

97-105

Informations de copyright

© 2021 The Authors. Early Intervention in Psychiatry published by John Wiley & Sons Australia, Ltd.

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Auteurs

Amelia Austin (A)

Eating Disorders Section, Department of Psychological Medicine, King's College London, London, UK.

Michaela Flynn (M)

Eating Disorders Section, Department of Psychological Medicine, King's College London, London, UK.

James Shearer (J)

Department of Health Services and Population Research, King's College London, London, UK.

Mike Long (M)

Kent Surrey Sussex Academic Health Science Network, Crawley, UK.

Karina Allen (K)

Eating Disorders Section, Department of Psychological Medicine, King's College London, London, UK.
South London and Maudsley NHS Foundation Trust, London, UK.

Victoria A Mountford (VA)

Eating Disorders Section, Department of Psychological Medicine, King's College London, London, UK.
South London and Maudsley NHS Foundation Trust, London, UK.
Maudsley Health, Abu Dhabi, UAE.

Danielle Glennon (D)

South London and Maudsley NHS Foundation Trust, London, UK.

Nina Grant (N)

South London and Maudsley NHS Foundation Trust, London, UK.

Amy Brown (A)

Sussex Partnership NHS Foundation Trust, Brighton, UK.

Mary Franklin-Smith (M)

Leeds and York Partnership NHS Trust, Leeds, UK.

Monique Schelhase (M)

Leeds and York Partnership NHS Trust, Leeds, UK.

William Rhys Jones (WR)

Leeds and York Partnership NHS Trust, Leeds, UK.

Gabrielle Brady (G)

Central and North West London NHS Foundation Trust, London, UK.

Nicole Nunes (N)

Central and North West London NHS Foundation Trust, London, UK.

Frances Connan (F)

Central and North West London NHS Foundation Trust, London, UK.

Kate Mahony (K)

North East London NHS Foundation Trust, London, UK.

Lucy Serpell (L)

North East London NHS Foundation Trust, London, UK.
Department of Clinical, Educational and Health Psychology, University College London, London, UK.

Ulrike Schmidt (U)

Eating Disorders Section, Department of Psychological Medicine, King's College London, London, UK.
South London and Maudsley NHS Foundation Trust, London, UK.

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