Sulfoquinovose is a select nutrient of prominent bacteria and a source of hydrogen sulfide in the human gut.
Journal
The ISME journal
ISSN: 1751-7370
Titre abrégé: ISME J
Pays: England
ID NLM: 101301086
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
received:
11
09
2020
accepted:
17
03
2021
revised:
01
03
2021
pubmed:
2
4
2021
medline:
23
9
2021
entrez:
1
4
2021
Statut:
ppublish
Résumé
Responses of the microbiota to diet are highly personalized but mechanistically not well understood because many metabolic capabilities and interactions of human gut microorganisms are unknown. Here we show that sulfoquinovose (SQ), a sulfonated monosaccharide omnipresent in green vegetables, is a selective yet relevant substrate for few but ubiquitous bacteria in the human gut. In human feces and in defined co-culture, Eubacterium rectale and Bilophila wadsworthia used recently identified pathways to cooperatively catabolize SQ with 2,3-dihydroxypropane-1-sulfonate as a transient intermediate to hydrogen sulfide (H
Identifiants
pubmed: 33790426
doi: 10.1038/s41396-021-00968-0
pii: 10.1038/s41396-021-00968-0
pmc: PMC8397734
doi:
Substances chimiques
Methylglucosides
0
sulfoquinovose
3458-06-8
Hydrogen Sulfide
YY9FVM7NSN
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2779-2791Subventions
Organisme : Austrian Science Fund FWF
ID : I 2320
Pays : Austria
Informations de copyright
© 2021. The Author(s).
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