Treatment of COVID-19: a review of current and prospective pharmacotherapies.

Adenosine Monophosphate / analogs & derivatives Alanine / analogs & derivatives Antibodies, Monoclonal, Humanized / therapeutic use Anticoagulants / therapeutic use Antiviral Agents / therapeutic use Azetidines / therapeutic use COVID-19 / therapy Colchicine / therapeutic use Dexamethasone / therapeutic use Glucocorticoids / therapeutic use Humans Immunization, Passive Immunologic Factors / therapeutic use Ivermectin / therapeutic use Janus Kinase Inhibitors / therapeutic use Platelet Aggregation Inhibitors / therapeutic use Purines / therapeutic use Pyrazoles / therapeutic use SARS-CoV-2 Sulfonamides / therapeutic use COVID-19 Drug Treatment COVID-19 Serotherapy
Anticoagulation Antivirals COVID-19 Immunomodulator

Journal

British journal of hospital medicine (London, England : 2005)
ISSN: 1750-8460
Titre abrégé: Br J Hosp Med (Lond)
Pays: England
ID NLM: 101257109

Informations de publication

Date de publication:
02 Mar 2021
Historique:
entrez: 1 4 2021
pubmed: 2 4 2021
medline: 13 4 2021
Statut: ppublish

Résumé

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread and have grave health and socioeconomic consequences worldwide. Researchers have raced to understand the pathophysiological mechanisms underpinning the disease caused by SARS-CoV-2 so that effective therapeutic targets can be discovered. This review summarises the key pharmacotherapies that are being investigated for treatment of COVID-19, including antiviral, immunomodulator and anticoagulation strategies.

Identifiants

DOI: 10.12968/hmed.2021.0112 PMID: 33792391
pubmed: 33792391
doi: 10.12968/hmed.2021.0112
doi:

Substances chimiques

Antibodies, Monoclonal, Humanized 0
Anticoagulants 0
Antiviral Agents 0
Azetidines 0
Glucocorticoids 0
Immunologic Factors 0
Janus Kinase Inhibitors 0
Platelet Aggregation Inhibitors 0
Purines 0
Pyrazoles 0
Sulfonamides 0
remdesivir 3QKI37EEHE
Adenosine Monophosphate 415SHH325A
bamlanivimab 45I6OFJ8QH
Ivermectin 70288-86-7
Dexamethasone 7S5I7G3JQL
tocilizumab I031V2H011
baricitinib ISP4442I3Y
sarilumab NU90V55F8I
Alanine OF5P57N2ZX
Colchicine SML2Y3J35T

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-9

Auteurs

Eleanor Quek (E)

Department of General Medicine, Barnet Hospital, Royal Free London NHS Foundation Trust, London, UK.

Hasan Tahir (H)

Department of Rheumatology and General Medicine, Barnet Hospital, Royal Free London NHS Foundation Trust, London, UK.
Division of Medicine, University College London, London, UK.

Poornima Kumar (P)

Department of Clinical Haematology, Barnet Hospital, Royal Free London NHS Foundation Trust, London, UK.

Robert Hastings (R)

Department of Respiratory Medicine, Barnet Hospital, Royal Free London NHS Foundation Trust, London, UK.

Rajeev Jha (R)

Department of Intensive Care, Barnet Hospital, Royal Free London NHS Foundation Trust, London, UK.

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Classifications MeSH

questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Ribonucléotides › Nucléotides adényliques › AMP › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Alanine › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Anticorps monoclonaux › Anticorps monoclonaux humanisés › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents hématologiques › Anticoagulants › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiviraux › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azétines › Azétidines › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Pneumopathie infectieuse › Pneumopathie virale › COVID-19 › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Composés hétérocycliques › Alcaloïdes › Colchicine › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Composés polycycliques › Composés à cycles fusionnés › Stéroïdes › Stéroïdes fluorés › Dexaméthasone › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Hormones, substituts d'hormones et antagonistes d'hormones › Hormones › Glucocorticoïdes › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Techniques d'investigation › Techniques immunologiques › Immunisation passive › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Facteurs immunologiques › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Composés chimiques organiques › Lactones › Ivermectine › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Inhibiteurs de protéines kinases › Inhibiteurs des Janus kinases › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents hématologiques › Antiagrégants plaquettaires › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Purines › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azoles › Pyrazoles › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Virus › Virus à ARN › Virus à ARN à brin positif › Nidovirales › Coronaviridae › Coronavirus › Betacoronavirus › Virus du SRAS › SARS-CoV-2 › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Sulfones › Sulfonamides › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Traitements médicamenteux de la COVID-19 › Treatment of COVID-19: a review of current and...
questionsmedicales.fr › Techniques d'investigation › Techniques immunologiques › Immunisation passive › Transfert adoptif › Sérothérapie COVID-19 › Treatment of COVID-19: a review of current and...