Malignant ulcer: a great mimicker of gastric plasmablastic lymphoma.
Gastrointestinal neoplasm
Non-Hodgkin lymphoma
Plasmablastic lymphoma
Journal
Clinical journal of gastroenterology
ISSN: 1865-7265
Titre abrégé: Clin J Gastroenterol
Pays: Japan
ID NLM: 101477246
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
received:
20
02
2021
accepted:
27
03
2021
pubmed:
3
4
2021
medline:
27
7
2021
entrez:
2
4
2021
Statut:
ppublish
Résumé
Plasmablastic lymphoma (PBL) is an uncommon human immunodeficiency virus (HIV)-associated lymphoma, with a predilection to develop in the oral cavity. It usually has a plasmablastic morphology with weak or no expression of B cell-associated markers. Among non-HIV patients, it tends to occur in the gastrointestinal (GI) tract, lymph nodes, and skin. We experience a 74-year-old male who presented with abdominal discomfort, altered bowel habit, loss of weight, and loss of appetite with a palpable abdominal mass. Upper endoscopy revealed multiple dish-like and raised nodular mass with a central ulcer in the stomach and duodenum. The histology was consistent with high-grade lymphoma of the plasmablastic type. The immunohistochemistry was positive for plasma cells marker of CD38 and CD138, but negative for the lymphocytic marker of CD45, as well as mature T and B cell marker of CD3 and CD20. Unfortunately, the patient succumbed due to sepsis without completion of his investigations and treatments.
Identifiants
pubmed: 33797037
doi: 10.1007/s12328-021-01409-3
pii: 10.1007/s12328-021-01409-3
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1027-1030Informations de copyright
© 2021. Japanese Society of Gastroenterology.
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