Functional Characterisation of Three Glycine
benzoate
coenzyme A
glycine N-acyltransferase (GLYAT)
glycine conjugation
hippurate
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
18 Mar 2021
18 Mar 2021
Historique:
received:
16
02
2021
revised:
15
03
2021
accepted:
15
03
2021
entrez:
3
4
2021
pubmed:
4
4
2021
medline:
22
4
2021
Statut:
epublish
Résumé
The glycine conjugation pathway in humans is involved in the metabolism of natural substrates and the detoxification of xenobiotics. The interactions between the various substrates in this pathway and their competition for the pathway enzymes are currently unknown. The pathway consists of a mitochondrial xenobiotic/medium-chain fatty acid: coenzyme A (CoA) ligase (ACSM2B) and glycine
Identifiants
pubmed: 33803916
pii: ijms22063129
doi: 10.3390/ijms22063129
pmc: PMC8003330
pii:
doi:
Substances chimiques
Acyl Coenzyme A
0
benzoyl-coenzyme A
6756-74-7
Acyltransferases
EC 2.3.-
glycine acyltransferase
EC 2.3.1.13
Glycine
TE7660XO1C
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : National Research Foundation of South Africa
ID : 117890
Références
J Am Med Inform Assoc. 2012 Mar-Apr;19(2):289-94
pubmed: 22319179
J Biol Chem. 1954 May;208(1):263-75
pubmed: 13174534
Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11553-8
pubmed: 26283387
Pharmacogenetics. 2000 Jun;10(4):355-69
pubmed: 10862526
Pharmacol Ther. 2012 Aug;135(2):151-67
pubmed: 22584143
Nucleic Acids Res. 2016 Jan 4;44(D1):D710-6
pubmed: 26687719
Annu Rev Biophys Biomol Struct. 2000;29:81-103
pubmed: 10940244
Mol Biol Evol. 2018 Jun 1;35(6):1547-1549
pubmed: 29722887
J Biochem Mol Toxicol. 2016 Mar;30(3):136-47
pubmed: 26484797
BMC Genomics. 2016 Jul 21;17:504
pubmed: 27444955
Br J Ind Med. 1988 Feb;45(2):127-32
pubmed: 3342195
Bioinformatics. 2007 Nov 1;23(21):2947-8
pubmed: 17846036
Biochem J. 1966 Jan;98(1):278-83
pubmed: 4223117
Toxicol Sci. 2004 Mar;78(1):1-2
pubmed: 15025107
Crit Rev Food Sci Nutr. 2017 Sep 22;57(14):3084-3103
pubmed: 26587821
J Biol Chem. 1967 Jun 25;242(12):2966-72
pubmed: 6027258
J Biochem Toxicol. 1994 Jun;9(3):153-8
pubmed: 7983681
Mol Genet Genomics. 2018 Oct;293(5):1279-1292
pubmed: 29948332
Pediatr Res. 1988 Jul;24(1):9-13
pubmed: 3137519
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2010 Jun;27(6):783-92
pubmed: 20349370
DNA Cell Biol. 1996 Apr;15(4):273-80
pubmed: 8639263
Xenobiotica. 1993 Feb;23(2):141-53
pubmed: 8498078
Gene. 2013 Feb 25;515(2):447-53
pubmed: 23237781
Nature. 2010 Sep 2;467(7311):52-8
pubmed: 20811451
Nature. 2020 May;581(7809):434-443
pubmed: 32461654
Xenobiotica. 1972 Jan;2(1):25-34
pubmed: 4211177
Science. 1981 Jan 23;211(4480):341-50
pubmed: 17748254
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2012;29(3):371-82
pubmed: 22264192
J Biochem Mol Toxicol. 2000;14(2):102-9
pubmed: 10630424
Genetics. 1995 Sep;141(1):413-29
pubmed: 8536987
J Pharmacol Exp Ther. 1993 Dec;267(3):1068-75
pubmed: 8263766
J Mol Evol. 1984;20(1):2-15
pubmed: 6429338
Biochem Biophys Res Commun. 2012 Apr 20;420(4):901-6
pubmed: 22475485
Biochem Biophys Res Commun. 1994 Dec 15;205(2):1373-9
pubmed: 7802672
Biochem Pharmacol. 1997 Apr 4;53(7):1041-7
pubmed: 9174118
Expert Opin Drug Metab Toxicol. 2007 Apr;3(2):159-68
pubmed: 17428148
Compr Rev Food Sci Food Saf. 2017 Sep;16(5):868-880
pubmed: 33371618
Nucleic Acids Res. 2012 Jul;40(Web Server issue):W452-7
pubmed: 22689647
J Clin Invest. 1957 Feb;36(2):297-302
pubmed: 13406041
Lancet. 2007 Nov 3;370(9598):1524-5
pubmed: 17980721
FEBS Lett. 2012 Aug 31;586(18):2813-9
pubmed: 22858376
Mol Biol Evol. 2011 Oct;28(10):2731-9
pubmed: 21546353
Biochimie. 2016 Jan;120:40-8
pubmed: 26253695
Am J Dis Child. 1975 Dec;129(12):1385-6
pubmed: 1199979
Free Radic Biol Med. 1999 Dec;27(11-12):1219-27
pubmed: 10641714
Xenobiotica. 2010 Dec;40(12):853-61
pubmed: 20925583
Biochem Med. 1974 May;10(1):15-23
pubmed: 4827843
Arch Intern Med. 1981 Feb 23;141(3 Spec No):333-42
pubmed: 7469624
Drug Metab Rev. 2014 Aug;46(3):343-61
pubmed: 24754494
Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11430-1
pubmed: 26372953
Clin Exp Pharmacol Physiol. 1998 Oct;25(10):776-82
pubmed: 9784915
Nucleic Acids Res. 2018 Jan 4;46(D1):D754-D761
pubmed: 29155950
Arch Biochem Biophys. 2005 Jan 1;433(1):212-26
pubmed: 15581578
Nature. 2015 Oct 1;526(7571):68-74
pubmed: 26432245
J Inherit Metab Dis. 2012 Nov;35(6):1021-9
pubmed: 22350545
Nat Methods. 2010 Apr;7(4):248-9
pubmed: 20354512
Am J Hum Genet. 2018 May 3;102(5):731-743
pubmed: 29706352
Gene. 2015 Oct 15;571(1):126-34
pubmed: 26149650
Mol Pharmacol. 1971 May;7(3):260-8
pubmed: 5571643
J Biochem Mol Toxicol. 2017 Nov;31(11):
pubmed: 28759163
Philos Trans R Soc Lond B Biol Sci. 2010 Oct 27;365(1556):3267-76
pubmed: 20855301
Evolution. 1985 Jul;39(4):783-791
pubmed: 28561359
Biochimie. 2021 Apr;183:30-34
pubmed: 33567294
Mol Cell Proteomics. 2013 Mar;12(3):575-86
pubmed: 23230277
Food Addit Contam. 2002 Jul;19(7):647-54
pubmed: 12113659
J Pharm Sci. 1965 Jul;54(7):959-67
pubmed: 5862532
Mol Biol Evol. 2004 Aug;21(8):1534-7
pubmed: 15140947
J Proteome Res. 2013 Apr 5;12(4):1527-46
pubmed: 23342949
Front Chem. 2017 Jun 19;5:41
pubmed: 28674689
Expert Opin Drug Metab Toxicol. 2013 Sep;9(9):1139-53
pubmed: 23650932
J Biol Chem. 1979 Aug 10;254(15):7230-7
pubmed: 457678
Genetics. 1989 Nov;123(3):585-95
pubmed: 2513255
PLoS One. 2011 Apr 06;6(4):e18507
pubmed: 21494681
J Theor Biol. 1984 Jun 7;108(3):451-7
pubmed: 6748701
J Phys Chem B. 2010 Dec 16;114(49):16209-13
pubmed: 21028874
Comput Appl Biosci. 1992 Jun;8(3):275-82
pubmed: 1633570
Genetics. 1993 Mar;133(3):693-709
pubmed: 8454210
Free Radic Biol Med. 2002 Jul 15;33(2):220-35
pubmed: 12106818
Biochem Med Metab Biol. 1986 Aug;36(1):98-105
pubmed: 3741707