The Effects of Time-Restricted Eating versus Standard Dietary Advice on Weight, Metabolic Health and the Consumption of Processed Food: A Pragmatic Randomised Controlled Trial in Community-Based Adults.


Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
23 03 2021
Historique:
received: 04 03 2021
revised: 16 03 2021
accepted: 18 03 2021
entrez: 3 4 2021
pubmed: 4 4 2021
medline: 2 6 2021
Statut: epublish

Résumé

Weight loss is key to controlling the increasing prevalence of metabolic syndrome (MS) and its components, i.e., central obesity, hypertension, prediabetes and dyslipidaemia. The goals of our study were two-fold. First, we characterised the relationships between eating duration, unprocessed and processed food consumption and metabolic health. During 4 weeks of observation, 213 adults used a smartphone application to record food and drink consumption, which was annotated for food processing levels following the NOVA classification. Low consumption of unprocessed food and low physical activity showed significant associations with multiple MS components. Second, in a pragmatic randomised controlled trial, we compared the metabolic benefits of 12 h time-restricted eating (TRE) to standard dietary advice (SDA) in 54 adults with an eating duration > 14 h and at least one MS component. After 6 months, those randomised to TRE lost 1.6% of initial body weight (SD 2.9,

Identifiants

pubmed: 33807102
pii: nu13031042
doi: 10.3390/nu13031042
pmc: PMC8004978
pii:
doi:

Types de publication

Journal Article Observational Study Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
ID : PZ00P3-167826

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Auteurs

Nicholas Edward Phillips (NE)

Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.

Julie Mareschal (J)

Service of Endocrinology, Diabetes, Nutrition and Therapeutic Education, Department of Medicine, Geneva University Hospitals (HUG), 1211 Geneva, Switzerland.

Nathalie Schwab (N)

Service of Endocrinology, Diabetes and Metabolism, Department of Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.
Department of General Internal Medicine, Bern University Hospital, Inselspital, University of Bern, 3010 Bern, Switzerland.
Institute of Primary Health Care (BIHAM), University of Bern, 3012 Bern, Switzerland.

Emily N C Manoogian (ENC)

Salk Institute for Biological Sciences, La Jolla, CA 92037, USA.

Sylvie Borloz (S)

Service of Paediatrics, Department Woman-Mother-Child, Lausanne University Hospital (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.

Giada Ostinelli (G)

Service of Endocrinology, Diabetes and Metabolism, Department of Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.
Quebec Heart and Lung Institute Research Center (Centre de Recherche de l'Institut Universitaire de Pneumologie et Cardiologie de Québec), Québec, QC G1V 4G5, Canada.
School of Nutrition (École de Nutrition), Laval University, Québec, QC G1V 0A6, Canada.

Aude Gauthier-Jaques (A)

Service of Endocrinology, Diabetes and Metabolism, Department of Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.

Sylvie Umwali (S)

Service of Endocrinology, Diabetes and Metabolism, Department of Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.
Service of Obstetrics, Department Woman-Mother-Child, Lausanne University Hospital (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.

Elena Gonzalez Rodriguez (E)

Interdisciplinary Center for Bone Diseases, Service of Rheumatology, Lausanne University Hospital (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.

Daniel Aeberli (D)

Department of Rheumatology and Immunology, Bern University Hospital, Inselspital and University of Bern, 3010 Bern, Switzerland.

Didier Hans (D)

Interdisciplinary Center for Bone Diseases, Service of Rheumatology, Lausanne University Hospital (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.

Satchidananda Panda (S)

Salk Institute for Biological Sciences, La Jolla, CA 92037, USA.

Nicolas Rodondi (N)

Department of General Internal Medicine, Bern University Hospital, Inselspital, University of Bern, 3010 Bern, Switzerland.
Institute of Primary Health Care (BIHAM), University of Bern, 3012 Bern, Switzerland.

Felix Naef (F)

Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.

Tinh-Hai Collet (TH)

Service of Endocrinology, Diabetes, Nutrition and Therapeutic Education, Department of Medicine, Geneva University Hospitals (HUG), 1211 Geneva, Switzerland.
Service of Endocrinology, Diabetes and Metabolism, Department of Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.

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