Safety of Ovaleap® (Follitropin Alfa) in Infertile Women Undergoing Superovulation for Assisted Reproductive Technologies: A Multinational Comparative, Prospective Cohort Study.
Adult
Female
Fertilization in Vitro
/ methods
Follicle Stimulating Hormone
/ therapeutic use
Follicle Stimulating Hormone, Human
/ adverse effects
Humans
Incidence
Infertility, Female
/ therapy
International Cooperation
Middle Aged
Multicenter Studies as Topic
Ovarian Hyperstimulation Syndrome
/ chemically induced
Ovulation Induction
/ methods
Prospective Studies
Recombinant Proteins
/ adverse effects
Regression Analysis
Reproductive Techniques, Assisted
Superovulation
Young Adult
Gonal-f®
Ovaleap®
follitropin alfa
live birth rate
ovarian hyperstimulation syndrome
pregnancy outcome
pregnancy rate
safety
Journal
Frontiers in endocrinology
ISSN: 1664-2392
Titre abrégé: Front Endocrinol (Lausanne)
Pays: Switzerland
ID NLM: 101555782
Informations de publication
Date de publication:
2021
2021
Historique:
received:
23
11
2020
accepted:
15
02
2021
entrez:
5
4
2021
pubmed:
6
4
2021
medline:
28
12
2021
Statut:
epublish
Résumé
Ovaleap Safety of Ovaleap A total of 408 women who were administered Ovaleap Findings from the SOFIA study indicate that the incidence proportions of OHSS and OHSS severity, as well as pregnancy and live birth rates, are similar between Ovaleap
Sections du résumé
Background
Ovaleap
Methods
Safety of Ovaleap
Results
A total of 408 women who were administered Ovaleap
Conclusions
Findings from the SOFIA study indicate that the incidence proportions of OHSS and OHSS severity, as well as pregnancy and live birth rates, are similar between Ovaleap
Identifiants
pubmed: 33815290
doi: 10.3389/fendo.2021.632674
pmc: PMC8010350
doi:
Substances chimiques
Follicle Stimulating Hormone, Human
0
Recombinant Proteins
0
follitropin alfa
0
Follicle Stimulating Hormone
9002-68-0
Types de publication
Comparative Study
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
632674Informations de copyright
Copyright © 2021 Kaplan, Levy-Toledano, Davies, Roy, Howles and Lass.
Déclaration de conflit d'intérêts
SK is an employee of Teva Pharmaceuticals Industries Ltd. RL-T is a consultant in RLT Media Consulting. RL-T was a consultant to Teva Pharmaceutical Industries Ltd. (and/or its affiliates), and then to Theramex at the time of study conduct. MD and DR are employees of the Drug Safety Research Unit (DSRU). The DSRU is an independent, academic research institution, and has received funds from Theramex for consulting on the study. CH and AL are consultants to Theramex.
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