Human PD-1
Arthritis, Rheumatoid
/ etiology
B-Lymphocyte Subsets
/ immunology
Biomarkers
CD4-Positive T-Lymphocytes
/ immunology
CD8-Positive T-Lymphocytes
/ immunology
Cell Communication
Cytokines
/ metabolism
Disease Susceptibility
Humans
Immunologic Memory
Interleukins
/ biosynthesis
Lymphocyte Activation
/ immunology
Programmed Cell Death 1 Receptor
/ metabolism
T-Lymphocyte Subsets
/ immunology
CD8
IL-21
PD-1
T cells
rheumatoid arthritis
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2021
2021
Historique:
received:
16
01
2021
accepted:
08
03
2021
entrez:
5
4
2021
pubmed:
6
4
2021
medline:
30
9
2021
Statut:
epublish
Résumé
Rheumatoid arthritis (RA) is a prototypical autoantibody-driven autoimmune disease in which T-B interactions play a critical role. Recent comprehensive analysis suggests that PD-1 CD8 IL-21-producing CD8 Identification of IL-21-producing PD-1
Sections du résumé
Background
Rheumatoid arthritis (RA) is a prototypical autoantibody-driven autoimmune disease in which T-B interactions play a critical role. Recent comprehensive analysis suggests that PD-1
Methods
CD8
Results
IL-21-producing CD8
Conclusions
Identification of IL-21-producing PD-1
Identifiants
pubmed: 33815416
doi: 10.3389/fimmu.2021.654623
pmc: PMC8017303
doi:
Substances chimiques
Biomarkers
0
Cytokines
0
Interleukins
0
PDCD1 protein, human
0
Programmed Cell Death 1 Receptor
0
interleukin-21
MKM3CA6LT1
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
654623Informations de copyright
Copyright © 2021 Higashioka, Yoshimura, Sakuragi, Ayano, Kimoto, Mitoma, Ono, Arinobu, Kikukawa, Yamada, Horiuchi, Akashi and Niiro.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Annu Rev Immunol. 2019 Apr 26;37:457-495
pubmed: 30676822
J Exp Med. 2013 Nov 18;210(12):2739-53
pubmed: 24218138
N Engl J Med. 2007 Sep 6;357(10):977-86
pubmed: 17804842
Trends Immunol. 2015 Dec;36(12):758-760
pubmed: 26588880
Arthritis Rheumatol. 2015 Sep;67(9):2476-81
pubmed: 25989153
Curr Opin Immunol. 2019 Dec;61:1-9
pubmed: 31374450
JCI Insight. 2019 Oct 17;4(20):
pubmed: 31536480
Blood. 2012 Apr 26;119(17):3997-4008
pubmed: 22403255
Arthritis Rheumatol. 2018 May;70(5):711-721
pubmed: 29381842
Trends Immunol. 2014 Sep;35(9):436-42
pubmed: 24998903
Arthritis Rheumatol. 2017 Sep;69(9):1850-1861
pubmed: 28564491
Immunity. 2011 Jan 28;34(1):108-21
pubmed: 21215658
Blood. 2013 Dec 5;122(24):3940-50
pubmed: 24159173
Annu Rev Med. 2018 Jan 29;69:301-318
pubmed: 29414259
Front Immunol. 2018 Jun 04;9:1226
pubmed: 29915585
Nat Immunol. 2019 Jul;20(7):928-942
pubmed: 31061532
Ann Rheum Dis. 2013 Aug;72(8):1420-4
pubmed: 23661491
Blood Adv. 2018 Aug 14;2(15):1889-1900
pubmed: 30087107
Ann Rheum Dis. 2019 Apr;78(4):539-550
pubmed: 30760472
Annu Rev Immunol. 2011;29:621-63
pubmed: 21314428
Sci Rep. 2016 Jul 29;6:30362
pubmed: 27468819
J Immunol. 2012 Apr 15;188(8):3734-44
pubmed: 22427637
Immunol Cell Biol. 2009 Nov-Dec;87(8):590-600
pubmed: 19721453
Arthritis Rheum. 2000 Dec;43(12):2619-33
pubmed: 11145019
Nature. 2017 Feb 1;542(7639):110-114
pubmed: 28150777
Science. 2009 Aug 21;325(5943):1006-10
pubmed: 19608860
J Immunol. 2013 Feb 15;190(4):1827-36
pubmed: 23325890
Arthritis Rheum. 2013 Dec;65(12):3063-72
pubmed: 24022618
Nat Rev Rheumatol. 2014 Nov;10(11):645-53
pubmed: 25072264
J Immunol. 1998 Dec 1;161(11):6390-7
pubmed: 9834130
Arthritis Rheumatol. 2015 Apr;67(4):988-99
pubmed: 25581113
Arthritis Rheum. 2008 Nov;58(11):3377-87
pubmed: 18975336
J Immunol. 2011 Apr 1;186(7):4200-12
pubmed: 21383243
J Clin Invest. 2018 Oct 1;128(10):4669-4681
pubmed: 30198907
Arthritis Res Ther. 2003;5(6):288-9
pubmed: 14680504
J Immunol. 2004 Nov 1;173(9):5361-71
pubmed: 15494482
J Exp Med. 2002 May 20;195(10):1325-36
pubmed: 12021312
Nature. 2007 Jun 7;447(7145):661-78
pubmed: 17554300
J Immunol. 2007 Apr 1;178(7):4112-9
pubmed: 17371966
Arthritis Rheumatol. 2015 Feb;67(2):363-71
pubmed: 25370956
Front Immunol. 2018 Aug 23;9:1924
pubmed: 30190721
J Clin Immunol. 2016 May;36 Suppl 1:34-9
pubmed: 26984851
Blood. 2013 Apr 25;121(17):3375-85
pubmed: 23476048
J Autoimmun. 2020 Jun;110:102392
pubmed: 31911013
Rheumatology (Oxford). 2019 Sep 1;58(9):1662-1673
pubmed: 31056653
Blood. 2008 Jun 1;111(11):5326-33
pubmed: 18276844
Immunity. 2009 Jul 17;31(1):158-69
pubmed: 19592276
J Exp Med. 2016 Oct 17;213(11):2281-2291
pubmed: 27670591