Bullous pemphigoid in patients receiving peritoneal dialysis: a case series and a literature survey.


Journal

Renal failure
ISSN: 1525-6049
Titre abrégé: Ren Fail
Pays: England
ID NLM: 8701128

Informations de publication

Date de publication:
Dec 2021
Historique:
entrez: 6 4 2021
pubmed: 7 4 2021
medline: 11 11 2021
Statut: ppublish

Résumé

Bullous pemphigoid (BP) is an autoimmune subepidermal blistering disease. Although several cases of BP in end-stage renal disease patients receiving peritoneal dialysis (PD) or hemodialysis have been reported, the incidence of BP in these patients remains unknown. We recently experienced three PD patients diagnosed with BP. The skin injury was likely to be a trigger of BP in all the three PD patients. Nifedipine and icodextrin exposures were possible factors directly or indirectly affecting the onset of BP, because they were common in the three cases. We also report that the incidence of BP in PD patients was 3/478.3 person-years in a single-center 10-year study. This case series with a literature survey describes that the skin and tissue injuries are potential triggers responsible for the onset of BP in dialysis patients and that the incidence of BP in these patients seems to be much higher than that in the general population.

Identifiants

pubmed: 33820495
doi: 10.1080/0886022X.2021.1910045
pmc: PMC8032334
doi:

Substances chimiques

Autoantibodies 0
Icodextrin 2NX48Z0A9G
Nifedipine I9ZF7L6G2L

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

651-657

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Auteurs

Kohkichi Morimoto (K)

Apheresis and Dialysis Center, School of Medicine, Keio University, Tokyo, Japan.

Tadashi Yoshida (T)

Apheresis and Dialysis Center, School of Medicine, Keio University, Tokyo, Japan.

Naoki Washida (N)

Department of Nephrology, School of Medicine, International University of Health and Welfare, Otawara, Japan.
Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan.

Kiyotaka Uchiyama (K)

Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan.

Takashin Nakayama (T)

Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan.

Hiroshi Itoh (H)

Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan.

Mototsugu Oya (M)

Apheresis and Dialysis Center, School of Medicine, Keio University, Tokyo, Japan.
Department of Urology, School of Medicine, Keio University, Tokyo, Japan.

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Classifications MeSH