Field infection of a gilt and its litter demonstrates vertical transmission and effect on reproductive failure caused by porcine circovirus type 3 (PCV3).
Abortion, Veterinary
/ virology
Animals
Circoviridae Infections
/ pathology
Circovirus
/ classification
Female
Fetus
/ virology
Infectious Disease Transmission, Vertical
/ veterinary
Phylogeny
Pregnancy
Pregnancy Complications, Infectious
/ veterinary
Stillbirth
/ veterinary
Swine
Swine Diseases
/ pathology
PCV3
Porcine circovirus 3
Putative infection
Reproductive failure
Viral load
Journal
BMC veterinary research
ISSN: 1746-6148
Titre abrégé: BMC Vet Res
Pays: England
ID NLM: 101249759
Informations de publication
Date de publication:
08 Apr 2021
08 Apr 2021
Historique:
received:
17
06
2020
accepted:
27
03
2021
entrez:
9
4
2021
pubmed:
10
4
2021
medline:
25
8
2021
Statut:
epublish
Résumé
PCV3 is a member of the Circovirus family, associated with disease and mortality in pigs. It is not clear whether PCV3 putatively causes clinical symptoms and disease. In the present case, we reported a gilt infected with PCV3 associated with reproductive failures, vertical transmission, tissue lesions, viral replication by in situ hybridization, and the hypothesis that some strains of PCV3 clade one are associated with reproductive failures at the field level. In May 2019, a pig farm in Colombia reported increased reproductive failures, and the presence of PCV3 in gilts and sows was established in a single form or coinfections, mainly with PCV2 and PPV7. Ten sows with a single infection with PCV3 were found, and one gilt with a pre-farrowing serum viral load above 10 This report confirms that PCV3 can cause disease at the field level, and putatively, in this case, we find the generation of reproductive failures. The ability of PCV3 to cause disease as a putative pathogen may be associated with the viral load present in the pig and the strain that is affecting the farm. For this case, we found that viral loads above 10
Sections du résumé
BACKGROUND
BACKGROUND
PCV3 is a member of the Circovirus family, associated with disease and mortality in pigs. It is not clear whether PCV3 putatively causes clinical symptoms and disease. In the present case, we reported a gilt infected with PCV3 associated with reproductive failures, vertical transmission, tissue lesions, viral replication by in situ hybridization, and the hypothesis that some strains of PCV3 clade one are associated with reproductive failures at the field level.
CASE PRESENTATION
METHODS
In May 2019, a pig farm in Colombia reported increased reproductive failures, and the presence of PCV3 in gilts and sows was established in a single form or coinfections, mainly with PCV2 and PPV7. Ten sows with a single infection with PCV3 were found, and one gilt with a pre-farrowing serum viral load above 10
CONCLUSIONS
CONCLUSIONS
This report confirms that PCV3 can cause disease at the field level, and putatively, in this case, we find the generation of reproductive failures. The ability of PCV3 to cause disease as a putative pathogen may be associated with the viral load present in the pig and the strain that is affecting the farm. For this case, we found that viral loads above 10
Identifiants
pubmed: 33832500
doi: 10.1186/s12917-021-02862-5
pii: 10.1186/s12917-021-02862-5
pmc: PMC8028087
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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