Nonbacterial thrombotic endocarditis in a patient with gastric cancer and SARS-CoV-2 infection.
Acute ischemic stroke
Gastric cancer
Nonbacterial thrombotic endocarditis
SARS-CoV-2
Journal
Clinical journal of gastroenterology
ISSN: 1865-7265
Titre abrégé: Clin J Gastroenterol
Pays: Japan
ID NLM: 101477246
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
received:
06
03
2021
accepted:
01
04
2021
pubmed:
10
4
2021
medline:
27
7
2021
entrez:
9
4
2021
Statut:
ppublish
Résumé
Nonbacterial thrombotic endocarditis, formerly known as marantic endocarditis, is a very rare complication of advanced malignancy and other hypercoagulable states in which sterile, fibrin vegetations develop on heart valve leaflets. The most common malignancies associated with this entity are lung, pancreatic and gastric cancer. It has also been described as a presentation of COVID-19, which is known to be frequently complicated with coagulopathy and thromboembolic events. We report the case of a 62 year-old female patient newly diagnosed with stage IV gastric cancer and acute SARS-CoV-2 infection, presenting with confusion and homonymous hemianopsia in the setting of multiple acute ischemic strokes complicating a nonbacterial thrombotic mitral endocarditis. Herein, we discuss the underlying pathophysiology and make the hypothesis that SARS-CoV-2 infection could have participated in the pathogenesis of nonbacterial thrombotic endocarditis in our patient suffering from a gastric cancer.
Identifiants
pubmed: 33835416
doi: 10.1007/s12328-021-01412-8
pii: 10.1007/s12328-021-01412-8
pmc: PMC8032844
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1031-1035Informations de copyright
© 2021. Japanese Society of Gastroenterology.
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