Mobile Protons Limit the Stability of Salt Bridges in the Gas Phase: Implications for the Structures of Electrosprayed Protein Ions.

Gases Ions Molecular Dynamics Simulation Proteins Protons Salts

Journal

The journal of physical chemistry. B
ISSN: 1520-5207
Titre abrégé: J Phys Chem B
Pays: United States
ID NLM: 101157530

Informations de publication

Date de publication:
22 04 2021
Historique:
pubmed: 14 4 2021
medline: 25 5 2021
entrez: 13 4 2021
Statut: ppublish

Résumé

Electrosprayed protein ions can retain native-like conformations. The intramolecular contacts that stabilize these compact gas-phase structures remain poorly understood. Recent work has uncovered abundant salt bridges in electrosprayed proteins. Salt bridges are zwitterionic BH

Identifiants

DOI: 10.1021/acs.jpcb.1c00944 PMID: 33848419
pubmed: 33848419
doi: 10.1021/acs.jpcb.1c00944
doi:

Substances chimiques

Gases 0
Ions 0
Proteins 0
Protons 0
Salts 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3803-3814

Auteurs

Lars Konermann (L)

Department of Chemistry, The University of Western Ontario, London, Ontario N6A 5B7, Canada.
ORCID: 0000-0002-5283-3165

Elnaz Aliyari (E)

Department of Chemistry, The University of Western Ontario, London, Ontario N6A 5B7, Canada.

Justin H Lee (JH)

Department of Chemistry, The University of Western Ontario, London, Ontario N6A 5B7, Canada.

Articles similaires

Atomic view of photosynthetic metabolite permeability pathways and confinement in synthetic carboxysome shells.

Daipayan Sarkar, Christopher Maffeo, Markus Sutter et al.
1.00
Photosynthesis Ribulose-Bisphosphate Carboxylase Carbon Dioxide Molecular Dynamics Simulation Cyanobacteria

Exploring structural diversity across the protein universe with The Encyclopedia of Domains.

Andy M Lau, Nicola Bordin, Shaun M Kandathil et al.
1.00
Databases, Protein Protein Domains Protein Folding Proteins Deep Learning

Drug repurposing against fucosyltransferase-2 via docking, STD-NMR, and molecular dynamic simulation studies.

Muhammad Atif, Humaira Zafar, Atia-Tul- Wahab et al.
1.00
Fucosyltransferases Drug Repositioning Molecular Docking Simulation Molecular Dynamics Simulation Humans

A head-to-head comparison of MM/PBSA and MM/GBSA in predicting binding affinities for the CB

Mei Qian Yau, Clarence W Y Liew, Jing Hen Toh et al.
1.00
Receptor, Cannabinoid, CB1 Ligands Molecular Dynamics Simulation Protein Binding Thermodynamics

Classifications MeSH

questionsmedicales.fr › Produits chimiques inorganiques › Gaz › Mobile Protons Limit the Stability of Salt...
questionsmedicales.fr › Produits chimiques inorganiques › Électrolytes › Ions › Mobile Protons Limit the Stability of Salt...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de dynamique moléculaire › Mobile Protons Limit the Stability of Salt...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Mobile Protons Limit the Stability of Salt...
questionsmedicales.fr › Phénomènes physiques › Particules élémentaires › Nucléons › Protons › Mobile Protons Limit the Stability of Salt...
questionsmedicales.fr › Produits chimiques inorganiques › Sels › Mobile Protons Limit the Stability of Salt...