On the power per mitochondrion and the number of associated active ATP synthases.
allometric power laws
cellular volumes
mitochondrial heat production
mitochondrial thermodynamics
number of ATP synthase molecules
scaling laws
Journal
Physical biology
ISSN: 1478-3975
Titre abrégé: Phys Biol
Pays: England
ID NLM: 101197454
Informations de publication
Date de publication:
14 06 2021
14 06 2021
Historique:
received:
30
11
2020
accepted:
14
06
2021
pubmed:
15
4
2021
medline:
3
11
2021
entrez:
14
4
2021
Statut:
epublish
Résumé
Recent experiments and thermodynamic arguments suggest that mitochondrial temperatures are higher than those of the cytoplasm. A "hot mitochondrion" calls for a closer examination of the energy balance that endows it with these claimed elevated temperatures. As a first step in this effort, we present here a semi-quantitative bookkeeping whereby, in one stroke, a formula is proposed that yields the rate of heat production in a typical mitochondrion and a formula for estimating the number of "
Identifiants
pubmed: 33853054
doi: 10.1088/1478-3975/abf7d9
doi:
Substances chimiques
Mitochondrial Proton-Translocating ATPases
EC 3.6.3.-
Types de publication
Letter
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2021 IOP Publishing Ltd.