Clinical and translational insights on premature ventricular contractions and PVC-induced cardiomyopathy.
Eccentric hypertrophy
Heart rate irregularity
LV dyssynchrony
Premature atrial contraction
Premature ventricular contraction
Journal
Progress in cardiovascular diseases
ISSN: 1873-1740
Titre abrégé: Prog Cardiovasc Dis
Pays: United States
ID NLM: 0376442
Informations de publication
Date de publication:
Historique:
received:
06
04
2021
accepted:
06
04
2021
pubmed:
16
4
2021
medline:
31
8
2021
entrez:
15
4
2021
Statut:
ppublish
Résumé
The medical community's understanding of the consequences of premature ventricular contractions (PVCs) and PVC-induced cardiomyopathy has been derived mostly from observational and large population-based studies. Due to the difficulty of predicting the development of PVC-cardiomyopathy, the acute and chronic cardiac effects of PVCs and the mechanism of PVC-cardiomyopathy have been derived from pre-clinical studies with large animal models. Recently, these studies have described myocardial substrates that could potentially increase morbidity and mortality in patients with frequent PVCs and PVC-cardiomyopathy. In this paper, we provide an up-to-date comprehensive review of these pre-clinical and clinical studies.
Identifiants
pubmed: 33857575
pii: S0033-0620(21)00038-4
doi: 10.1016/j.pcad.2021.04.001
pmc: PMC9192164
mid: NIHMS1699675
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
17-27Subventions
Organisme : BLRD VA
ID : I01 BX004861
Pays : United States
Organisme : NHLBI NIH HHS
ID : R56 HL133182
Pays : United States
Organisme : BLRD VA
ID : I01 BX004859
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL139874
Pays : United States
Organisme : NHLBI NIH HHS
ID : R34 HL138110
Pays : United States
Organisme : BLRD VA
ID : IS1 BX005574
Pays : United States
Informations de copyright
Published by Elsevier Inc.
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