Prostaglandin E
Inflammation
Matrix degeneration
Osteoarthritis
Pain
Prostaglandin E(2)
Synovium
Journal
Prostaglandins & other lipid mediators
ISSN: 1098-8823
Titre abrégé: Prostaglandins Other Lipid Mediat
Pays: United States
ID NLM: 9808648
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
received:
20
01
2021
revised:
31
03
2021
accepted:
06
04
2021
pubmed:
16
4
2021
medline:
21
1
2022
entrez:
15
4
2021
Statut:
ppublish
Résumé
Characteristic features of osteoarthritis (OA) are joint pain and cartilage degeneration. The degeneration is caused by excess induction of matrix metalloproteinases (MMPs) and the pain is caused by nerve growth factor (NGF)-dependent nerve invasion into synovial tissue in addition to nociceptive pain by prostaglandin (PG)E
Identifiants
pubmed: 33857603
pii: S1098-8823(21)00025-3
doi: 10.1016/j.prostaglandins.2021.106550
pii:
doi:
Substances chimiques
IL1B protein, human
0
Interleukin-1beta
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
106550Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.