Rectal organoid morphology analysis (ROMA) as a promising diagnostic tool in cystic fibrosis.

Cystic Fibrosis / diagnostic imaging Cystic Fibrosis Transmembrane Conductance Regulator / genetics Humans Mutation Organoids
cystic fibrosis

Journal

Thorax
ISSN: 1468-3296
Titre abrégé: Thorax
Pays: England
ID NLM: 0417353

Informations de publication

Date de publication:
11 2021
Historique:
received: 13 10 2020
revised: 03 02 2021
accepted: 09 03 2021
pubmed: 17 4 2021
medline: 18 1 2022
entrez: 16 4 2021
Statut: ppublish

Résumé

Diagnosing cystic fibrosis (CF) when sweat chloride is not in the CF range and less than 2 disease-causing

Identifiants

DOI: 10.1136/thoraxjnl-2020-216368 PMID: 33859053
pubmed: 33859053
pii: thoraxjnl-2020-216368
doi: 10.1136/thoraxjnl-2020-216368
doi:

Substances chimiques

Cystic Fibrosis Transmembrane Conductance Regulator 126880-72-6

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1146-1149

Informations de copyright

© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Senne Cuyx (S)

Department of Development and Regeneration, Woman and Child Unit, CF Research Lab, KU Leuven, Leuven, Flanders, Belgium.
Department of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Leuven, Flanders, Belgium.
ORCID: 0000-0002-6473-8966

Anabela Santo Ramalho (AS)

Department of Development and Regeneration, Woman and Child Unit, CF Research Lab, KU Leuven, Leuven, Flanders, Belgium.
ORCID: 0000-0003-3143-3661

Nikky Corthout (N)

VIB Bio Imaging Core, VIB KU Leuven Center for Brain & Disease Research, Leuven, Belgium.
Department for Neuroscience, KU Leuven, Leuven, Flanders, Belgium.

Steffen Fieuws (S)

Interuniversity Center for Biostatistics and Statistical Bioinformatics, KU Leuven, Leuven, Flanders, Belgium.
Interuniversity Center for Biostatistics and Statistical Bioinformatics, Hasselt University, Hasselt, Limburg, Belgium.

Eva Fürstová (E)

Department of Pediatrics, 2nd Faculty of Medicine, Motol University Hospital, Praha, Czech Republic.

Kaline Arnauts (K)

Department of Chronic Diseases and Metabolism (CHROMETA), Translational Research Center for Gastrointestinal Disorders (TARGID), KU Leuven, Leuven, Flanders, Belgium.
Department of Development and Regeneration, Stem Cell Institute Leuven (SCIL), KU Leuven, Leuven, Flanders, Belgium.

Marc Ferrante (M)

Department of Chronic Diseases and Metabolism (CHROMETA), Translational Research Center for Gastrointestinal Disorders (TARGID), KU Leuven, Leuven, Flanders, Belgium.
Department of Gastroenterology and Hepatology, University Hospital of Leuven, Leuven, Flanders, Belgium.

Catherine Verfaillie (C)

Department of Development and Regeneration, Stem Cell Institute Leuven (SCIL), KU Leuven, Leuven, Flanders, Belgium.

Sebastian Munck (S)

VIB Bio Imaging Core, VIB KU Leuven Center for Brain & Disease Research, Leuven, Belgium.
Department for Neuroscience, KU Leuven, Leuven, Flanders, Belgium.

Mieke Boon (M)

Department of Development and Regeneration, Woman and Child Unit, CF Research Lab, KU Leuven, Leuven, Flanders, Belgium.
Department of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Leuven, Flanders, Belgium.

Marijke Proesmans (M)

Department of Development and Regeneration, Woman and Child Unit, CF Research Lab, KU Leuven, Leuven, Flanders, Belgium.
Department of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Leuven, Flanders, Belgium.

Lieven Dupont (L)

Department of Chronic Diseases, Metabolism and Ageing; Pneumology, University Hospital of Leuven, Leuven, Flanders, Belgium.
Department of Respiratory Diseases, University Hospital of Leuven, Leuven, Flanders, Belgium.

Kris De Boeck (K)

Department of Development and Regeneration, Woman and Child Unit, CF Research Lab, KU Leuven, Leuven, Flanders, Belgium.
Department of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Leuven, Flanders, Belgium.

François Vermeulen (F)

Department of Development and Regeneration, Woman and Child Unit, CF Research Lab, KU Leuven, Leuven, Flanders, Belgium francois.vermeulen@uzleuven.be.
Department of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Leuven, Flanders, Belgium.
ORCID: 0000-0003-2303-2470

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Malformations et maladies congénitales, héréditaires et néonatales › Maladies néonatales › Mucoviscidose › Rectal organoid morphology analysis (ROMA) as...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Pompes ioniques › Transporteurs d'anions › Transporteurs d'anions organiques › Transporteurs d'anions organiques ATP-dépendants › Protéines associées à la multirésistance aux médicaments › Protéine CFTR › Rectal organoid morphology analysis (ROMA) as...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Rectal organoid morphology analysis (ROMA) as...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › Rectal organoid morphology analysis (ROMA) as...
questionsmedicales.fr › Tissus › Organoïdes › Rectal organoid morphology analysis (ROMA) as...