Parenchymal-sparing hepatectomy with hepatic vein resection and reconstruction.


Journal

Acta chirurgica Belgica
ISSN: 0001-5458
Titre abrégé: Acta Chir Belg
Pays: England
ID NLM: 0370571

Informations de publication

Date de publication:
Oct 2022
Historique:
pubmed: 17 4 2021
medline: 28 9 2022
entrez: 16 4 2021
Statut: ppublish

Résumé

Hepatectomy remains the most important treatment modality for most malignant liver tumors. Vascular involvement stays a reason for unresectability or major parenchymal resection. A possible way to avoid this is parenchymal-sparing hepatectomy (PSHX) with vascular resection and reconstruction (HVRR). In this article, we aim to demonstrate the specific role of this technique in avoiding post-hepatectomy liver failure (PHLF). A retrospective analysis of 10 patients who underwent HVRR was conducted. In our cohort, there was no perioperative mortality. Two patients suffered a Clavien-Dindo grade 3a complication and none had clinically significant PHLF. Estimated FLRF was significantly higher in HVRR compared to major hepatectomy after portal vein embolization ( Instead of focusing on inducing liver remnant hypertrophy, preserving parenchyma through HVRR can be an interesting treatment strategy. It can be performed with an acceptable operative risk. Calculations of FLRF (using HBS) suggest that this approach is able to reduce the risk for PHLF and related morbidity or mortality.

Sections du résumé

BACKGROUND UNASSIGNED
Hepatectomy remains the most important treatment modality for most malignant liver tumors. Vascular involvement stays a reason for unresectability or major parenchymal resection. A possible way to avoid this is parenchymal-sparing hepatectomy (PSHX) with vascular resection and reconstruction (HVRR). In this article, we aim to demonstrate the specific role of this technique in avoiding post-hepatectomy liver failure (PHLF).
METHODS UNASSIGNED
A retrospective analysis of 10 patients who underwent HVRR was conducted.
RESULTS UNASSIGNED
In our cohort, there was no perioperative mortality. Two patients suffered a Clavien-Dindo grade 3a complication and none had clinically significant PHLF. Estimated FLRF was significantly higher in HVRR compared to major hepatectomy after portal vein embolization (
CONCLUSIONS UNASSIGNED
Instead of focusing on inducing liver remnant hypertrophy, preserving parenchyma through HVRR can be an interesting treatment strategy. It can be performed with an acceptable operative risk. Calculations of FLRF (using HBS) suggest that this approach is able to reduce the risk for PHLF and related morbidity or mortality.

Identifiants

pubmed: 33860723
doi: 10.1080/00015458.2021.1915021
pii: 10.1080/00015458.2021.1915021
doi:

Substances chimiques

Aniline Compounds 0
Technetium 7440-26-8
mebrofenin 7PV0B6ED98
Glycine TE7660XO1C

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

334-340

Auteurs

Thomas Apers (T)

Department of Hepatobiliary and Transplantation Surgery, Antwerp University Hospital, Edegem, Belgium.

Bart Hendrikx (B)

Department of Hepatobiliary and Transplantation Surgery, Antwerp University Hospital, Edegem, Belgium.

Bart Bracke (B)

Department of Hepatobiliary and Transplantation Surgery, Antwerp University Hospital, Edegem, Belgium.

Vera Hartman (V)

Department of Hepatobiliary and Transplantation Surgery, Antwerp University Hospital, Edegem, Belgium.

Geert Roeyen (G)

Department of Hepatobiliary and Transplantation Surgery, Antwerp University Hospital, Edegem, Belgium.

Dirk Ysebaert (D)

Department of Hepatobiliary and Transplantation Surgery, Antwerp University Hospital, Edegem, Belgium.

Bart Op de Beeck (B)

Department of Radiology, Antwerp University Hospital, Edegem, Belgium.

Thiery Chapelle (T)

Department of Hepatobiliary and Transplantation Surgery, Antwerp University Hospital, Edegem, Belgium.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH