Association of sugary drink consumption with all-cause and cause-specific mortality: the Japan Public Health Center-based Prospective Study.
JPHC study
Japan
Mortality
Prospective cohort study
Sugary drinks
Journal
Preventive medicine
ISSN: 1096-0260
Titre abrégé: Prev Med
Pays: United States
ID NLM: 0322116
Informations de publication
Date de publication:
07 2021
07 2021
Historique:
received:
15
12
2020
revised:
11
03
2021
accepted:
11
04
2021
pubmed:
19
4
2021
medline:
29
6
2021
entrez:
18
4
2021
Statut:
ppublish
Résumé
Few epidemiologic studies have assessed the associations of sugary drink consumption with mortality outcomes among Asian populations. This study included 70,486 participants in the Japan Public Health Center-based Prospective Study at the age of 45-74 years in 1995-1999. A validated food frequency questionnaire was used to assess the consumption of sugary drinks. We estimated the risk of total and cause-specific mortality associated with sugary drink consumption using Cox proportional hazards regression model. Mean follow-up was 17.1 years, during which 11,811 deaths were documented. Sugary drink consumption was associated with higher total mortality, with multivariate HR of 1.06 (95% CI 1.00-1.13) for quintile 3, 1.07 (95% CI 1.01-1.13) for quintile 4, and 1.15 (95% CI 1.09-1.22) for quintile 5, compared with quintile 1 (P < 0.001 for trend). Additionally, positive associations with cause-specific mortality were observed, including death from circulatory system diseases (quintile 5 vs quintile 1; HR, 1.23; 95% CI 1.09-1.38) and heart disease (quintile 5 vs quintile 1; HR, 1.35; 95% CI 1.14-1.60). In this large Japanese prospective study, sugary drink consumption was associated with all-cause and cause-specific mortality.
Sections du résumé
BACKGROUND
Few epidemiologic studies have assessed the associations of sugary drink consumption with mortality outcomes among Asian populations.
METHODS
This study included 70,486 participants in the Japan Public Health Center-based Prospective Study at the age of 45-74 years in 1995-1999. A validated food frequency questionnaire was used to assess the consumption of sugary drinks. We estimated the risk of total and cause-specific mortality associated with sugary drink consumption using Cox proportional hazards regression model.
RESULTS
Mean follow-up was 17.1 years, during which 11,811 deaths were documented. Sugary drink consumption was associated with higher total mortality, with multivariate HR of 1.06 (95% CI 1.00-1.13) for quintile 3, 1.07 (95% CI 1.01-1.13) for quintile 4, and 1.15 (95% CI 1.09-1.22) for quintile 5, compared with quintile 1 (P < 0.001 for trend). Additionally, positive associations with cause-specific mortality were observed, including death from circulatory system diseases (quintile 5 vs quintile 1; HR, 1.23; 95% CI 1.09-1.38) and heart disease (quintile 5 vs quintile 1; HR, 1.35; 95% CI 1.14-1.60).
CONCLUSION
In this large Japanese prospective study, sugary drink consumption was associated with all-cause and cause-specific mortality.
Identifiants
pubmed: 33865863
pii: S0091-7435(21)00145-6
doi: 10.1016/j.ypmed.2021.106561
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
106561Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.