Late outcome after surgical and topical treatment for Aspergillus mediastinitis after heart transplantation.
Aspergillus fumigatus
fungal infection
heart transplant
mediastinitis
mycotic aneurysm
topical treatment
Journal
Journal of cardiac surgery
ISSN: 1540-8191
Titre abrégé: J Card Surg
Pays: United States
ID NLM: 8908809
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
revised:
04
01
2021
received:
28
10
2020
accepted:
09
02
2021
pubmed:
22
4
2021
medline:
11
6
2021
entrez:
21
4
2021
Statut:
ppublish
Résumé
The 7-year long-term survival after Aspergillus fumigatus mediastinitis after heart transplantation, an uncommonly described condition, is herein reported. A 66-year-old male developed an infection with A. fumigatus covering the entire thoracic cavity with a fungal turf after orthotopic heart transplantation. Repeated surgical removal of infectious and necrotic tissue together with innovative topical treatment using voriconazole and chlorhexidine combined with systemic antifungal treatment, helped in controlling the infection. Definitive wound closure was achieved by standard sternal refixation and latissimus dorsi muscle flap plasty. Survival after A. fumigatus mediastinitis after heart transplantation was achieved with sequential debridement in combination with topical application of antifungal agents.
Substances chimiques
Voriconazole
JFU09I87TR
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
2558-2561Subventions
Organisme : The EurAsia Heart Foundation, Zürich, Switzerland
ID : There is no specific Grant number. The EurAsia Hea
Informations de copyright
© 2021 Wiley Periodicals LLC.
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