Introduction, Transmission Dynamics, and Fate of Early Severe Acute Respiratory Syndrome Coronavirus 2 Lineages in Santa Clara County, California.


Journal

The Journal of infectious diseases
ISSN: 1537-6613
Titre abrégé: J Infect Dis
Pays: United States
ID NLM: 0413675

Informations de publication

Date de publication:
15 07 2021
Historique:
received: 22 01 2021
accepted: 19 04 2021
pubmed: 25 4 2021
medline: 23 7 2021
entrez: 24 4 2021
Statut: ppublish

Résumé

We combined viral genome sequencing with contact tracing to investigate introduction and evolution of severe acute respiratory syndrome coronavirus 2 lineages in Santa Clara County, California, from 27 January to 21 March 2020. From 558 persons with coronavirus disease 2019, 101 genomes from 143 available clinical samples comprised 17 lineages, including SCC1 (n = 41), WA1 (n = 9; including the first 2 reported deaths in the United States, with postmortem diagnosis), D614G (n = 4), ancestral Wuhan Hu-1 (n = 21), and 13 others (n = 26). Public health intervention may have curtailed the persistence of lineages that appeared transiently during February and March. By August, only D614G lineages introduced after 21 March were circulating in Santa Clara County.

Identifiants

pubmed: 33893501
pii: 6242512
doi: 10.1093/infdis/jiab199
pmc: PMC8135363
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

207-217

Subventions

Organisme : NIAID NIH HHS
ID : R21 AI129455
Pays : United States
Organisme : Innovative Genomics Institute
Organisme : NIH HHS
ID : R33-AI129455
Pays : United States
Organisme : CIHR
Pays : Canada

Informations de copyright

© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

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Auteurs

Elsa Villarino (E)

County of Santa Clara Public Health Department, San Jose, California, USA.

Xianding Deng (X)

Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California, USA.
UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA.

Carol A Kemper (CA)

El Camino Hospital, Mountain View and Los Gatos, California, USA.

Michelle A Jorden (MA)

Office of the Medical Examiner-Coroner, County of Santa Clara, San Jose, California, USA.

Brandon Bonin (B)

County of Santa Clara Public Health Department, San Jose, California, USA.

Sarah L Rudman (SL)

County of Santa Clara Public Health Department, San Jose, California, USA.

George S Han (GS)

County of Santa Clara Public Health Department, San Jose, California, USA.

Guixia Yu (G)

Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California, USA.
UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA.

Candace Wang (C)

Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California, USA.
UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA.

Scot Federman (S)

Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California, USA.
UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA.

Brian Bushnell (B)

Lawrence Berkeley National Laboratory, Berkeley, California, USA.

Debra A Wadford (DA)

Viral and Rickettsial Disease Laboratory, California Department of Public Health, Richmond, California, USA.

Wen Lin (W)

County of Santa Clara Public Health Department, San Jose, California, USA.

Ying Tao (Y)

Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Clinton R Paden (CR)

Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Julu Bhatnagar (J)

Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Tara MacCannell (T)

County of Santa Clara Public Health Department, San Jose, California, USA.

Suxiang Tong (S)

Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Joshua Batson (J)

Chan Zuckerberg Biohub, San Francisco, California, USA.
The Public Health Company, Goleta, California, USA.

Charles Y Chiu (CY)

Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California, USA.
UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA.
Department of Medicine, Division of Infectious Diseases, University of California, San Francisco, San Francisco, California, USA.
Innovative Genomics Institute, University of California, Berkeley, Berkeley, California, USA.

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